Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157424 | 0.89 | POLB (0.41) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL8816003 | 0.89 | POLB (0.60) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL43414 | 0.88 | POLB (0.41) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL2435515 | 0.85 | POLB (0.41) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL6052790 | 0.83 | SMN1; SMN2 (0.40) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL1888896 | 0.83 | ALDH1A1 (0.37) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL8328957 | 0.83 | ALDH1A1 (0.39) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL1746858 | 0.82 | ALDH1A1 (0.35) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL2050169 | 0.80 | POLB (0.35) | POLBRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL12092095 | 0.79 | LMNA (0.42) | POLBRAB9AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150293106-A1 | DIAROMATIC AMINO ACID SUBSTRATE FOR CATHEPSIN DETECTION | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-10-15 | — | — | US | claimed |
| EP-1813614-B1 | Cytotoxic agents comprising new tomaymycin derivatives | SANOFI SA (FR) | 2011-10-05 | — | — | EP | claimed |
| US-20110160126-A1 | Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders | OSPREY PHARMACEUTICALS LIMITED (CA) | 2011-06-30 | — | — | US | claimed |
| US-7514078-B2 | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies | CORNELL RESEARCH FOUNDATION, INC. (US) | 2009-04-07 | — | — | US | claimed |
| US-7166702-B1 | Cytotoxic conjugates comprising a chemokine receptor targeting agent | OSPREY PHARMACEUTICALS, LTD. (CA) | 2007-01-23 | — | — | US | claimed |
| EP-1346731-B1 | Conjugates for treating inflammatory disorders and associated tissue damage | OSPREY PHARMACEUTICALS LTD (CA) | 2006-12-06 | — | — | EP | claimed |
| US-20060198820-A1 | Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders | OSPREY PHARMACEUTICALS LIMITED (CA) | 2006-09-07 | — | — | US | claimed |
| EP-0832201-B1 | A SAMPLE PRESENTATION APPARATUS FOR MASS SPECTROMETRY | UNIV ARIZONA (US) | 2005-10-05 | — | — | EP | claimed |
| US-6924268-B2 | Method for inactivating gonadotrophs | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-08-02 | — | — | US | claimed |
| EP-1346731-A1 | Conjugates for treating inflammatory disorders and associated tissue damage | Osprey Pharmaceuticals Limited (CA) | 2003-09-24 | — | — | EP | claimed |
| EP-1098664-A2 | CONJUGATES FOR TREATING INFLAMMATORY DISORDERS AND ASSOCIATED TISSUE DAMAGE | Osprey Pharmaceuticals Limited (CA) | 2001-05-16 | — | — | EP | claimed |
| US-6103881-A | HORMONE/NUCLEASE CONJUGATE CAPABLE OF BINDING TO GONADOTROPH CELLS AND PREVENTING SECRETION OF GONADOTROPHINS; TREATMENT OF HORMONE RELATED DISORDERS SUCH AS BREAST AND PROSTATE CANCER; STERILIZATION OF ANIMALS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-08-15 | — | — | US | claimed |
| US-6093541-A | WITH METAL PRESENTATION SURFACE HAVING IMMOBILIZED COMPLEX OF TETHERING MOLECULE AND DIGESTION MOLECULE; FOR RAPID AND EFFICIENT ANALYSIS OF BIOMOLECULES USING MATRIX-ASSISTED LASER DESORPTION/IONIZATION TECHNIQUE | ARIZONA STATE UNIVERSITY BOARD OF REGENTS (US) | 2000-07-25 | — | — | US | claimed |
| WO-2000021576-A2 | METHOD FOR VIEWING TUMOR TISSUE LOCATED WITHIN A BODY CAVITY | FLUORO PROBE, INC. (US) | 2000-04-20 | — | — | WO | claimed |
| WO-2000004926-A2 | CONJUGATES FOR TREATING INFLAMMATORY DISORDERS AND ASSOCIATED TISSUE DAMAGE | OSPREY PHARMACEUTICALS LIMITED (CA) | 2000-02-03 | — | — | WO | claimed |
| US-6004770-A | MASS SPECTROMETRY SAMPLE PRESENTATION APPARATUSES DERIVATIZED WITH COMPLEXES INCLUDING AT LEAST ONE MOLECULE WHICH MODIFIES A BIOMOLECULE | ARIZONA STATE UNIVERSITY BOARD OF REGENTS (US) | 1999-12-21 | — | — | US | claimed |
| US-5631229-A | ADMINISTERING A PEPTIDE HORMONE/TOXIN CONJUGATE WHICH SELECTIVELY BINDS TO RECEPTORS IN THE PITUITARY GLAND; ANTIFERTILITY AGENTS; STERILIZATION; SIDE EFFECT REDUCTION; CATTLE | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-05-20 | — | — | US | claimed |
| US-5492893-A | STERILIZATION OF ANIMALS; THERAPY OD SEX HORMONE RELATEDDISEASES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-02-20 | — | — | US | claimed |
| US-5488036-A | GONADOTROPHINS IN CELLS FOR POLYPEPTIDE HORMONES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-01-30 | — | — | US | claimed |
| US-5378688-A | Conjugating luteinizing hormone releasing hormone to plant, bacterialo or chemical toxins | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150293106-A1 | DIAROMATIC AMINO ACID SUBSTRATE FOR CATHEPSIN DETECTION | CTSV, CTSZ, CTSH | POLB 2845/4885RAB9A 1562/4885ALDH1A1 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.