Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888896 | 0.90 | ALDH1A1 (0.37) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL561821 | 0.86 | RAB9A (0.37) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL342420 | 0.83 | POLB (0.45) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL1746858 | 0.81 | ALDH1A1 (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5133715 | 0.80 | LMNA (0.36) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL4070360 | 0.78 | LMNA (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL14157424 | 0.78 | POLB (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL4445539 | 0.78 | NPC1 (0.36) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7201002 | 0.77 | POLB (0.32) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL6052790 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698040-A4 | LHRH ANTAGONISTS | BIOTECH AUSTRALIA PTY LTD (AU) | 1999-01-07 | — | — | EP | disclosed |
| EP-0698040-A1 | LHRH ANTAGONISTS | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994028015-A1 | LHRH ANTAGONISTS | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 1994-12-08 | — | — | WO | disclosed |