Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibemethine SCHEMBL10542007 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| Dibemethine SCHEMBL276863 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| Dibemethine SCHEMBL2139708 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| SCHEMBL22305213 | 0.79 | KDM4E (0.61) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| Dibemethine SCHEMBL9416516 | 0.79 | NPC1 (0.63) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| Dibemethine SCHEMBL9416520 | 0.79 | NPC1 (0.63) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| Dibemethine SCHEMBL28224227 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| SCHEMBL13052123 | 0.78 | TSHR (0.61) | ALDH1A1KDM4ETSHRCARM1PRMT6 | |
| SCHEMBL16062223 | 0.78 | ACHE (0.64) | ALDH1A1KDM4EACHEBCHENPC1 | |
| SCHEMBL4182133 | 0.78 | RAB9A (0.52) | ALDH1A1KDM4ETSHRCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750180-B2 | Process for the preparation of N-phosphonomethylglycine and derivatives thereof | MONSANTO TECHNOLOGY LLC (US) | 2010-07-06 | — | — | US | disclosed |
| EP-1664068-A2 | PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF | Monsanto Technology, LLC (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050054871-A1 | Process for the preparation of N-phosphonomethylglycine and derivatives thereof | MONSANTO TECHNOLOGY LLC | 2005-03-10 | — | — | US | disclosed |
| WO-2005019230-A2 | PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF | MONSANTO TECHNOLOGY LLC (US) | 2005-03-03 | — | — | WO | disclosed |
| US-4368162-A | Process for producing aminomethylphosphonic acid | CIBA-GEIGY CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054871-A1 | Process for the preparation of N-phosphonomethylglycine and derivatives thereof | PHOSPHO1, GNE, MPHOSPH6 | ALDH1A1 4362/4885KDM4E 2415/4885TSHR 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.