SCHEMBL3425358

SCHEMBL3425358

N#CC(C#N)C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
TSHR P16473 2/20 0.39
CYP1A2 P05177 2/20 0.39
HTR2A P28223 1/20 0.37
PIM1 P11309 1/20 0.35
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
POLB P06746 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A3 O75751 1/20 0.33
ATM Q13315 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13951178 0.78 MEN1 (0.35) TSHRCYP1A2PIM1BCHEPOLB
SCHEMBL132885 0.77 CYP1A2 (0.31) TSHRCYP1A2
SCHEMBL17081293 0.76 ALDH1A1 (0.34)
SCHEMBL10781097 0.75 GPR3 (0.36) GPR3TSHRCYP1A2HTR2APIM1
SCHEMBL5998334 0.75 CHRNB4 (0.41) GPR3TSHRCYP1A2HTR2APIM1
SCHEMBL9634111 0.69 CYP1A2 (0.47) GPR3TSHRCYP1A2HTR2ABCHE
SCHEMBL6675583 0.69 GPR3 (0.46) GPR3TSHRCYP1A2HTR2ABCHE
SCHEMBL6648437 0.69 PIM1 (0.56) GPR3CYP1A2HTR2APIM1BCHE
SCHEMBL3919889 0.69 GPR3 (0.46) GPR3TSHRCYP1A2HTR2ABCHE
SCHEMBL5032105 0.69 CYP1A2 (0.47) GPR3TSHRCYP1A2HTR2ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110361942-B Electrophotographic photoreceptor, process cartridge, image forming apparatus, and imide compound 富士胶片商业创新有限公司 2024-04-05 CN disclosed
US-10732526-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-08-04 US disclosed
US-10635009-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-28 US disclosed
US-20190332023-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-10-31 US disclosed
US-20180057428-A1 Enhancing thermal stability of bulk heterojunction solar cells with fluorenone derivatives HONG KONG BAPTIST UNIVERSITY (HK) 2018-03-01 US disclosed
EP-1808223-B1 SOLVENT COMPOSITION ADEKA CORP (JP) 2012-11-07 EP disclosed
EP-1716577-B1 POLYMER SYSTEM WITH A CHARGE CARRIER MOBILITY THAT CAN BE ADJUSTED IN A DEFINED MANNER FRAUNHOFER GES FORSCHUNG (DE) 2012-08-01 EP disclosed
CN-100588452-C Solvent composition ADEKA CORP 2010-02-10 CN disclosed
US-7648651-B2 Solvent composition ADEKA CORPORATION (JP) 2010-01-19 US disclosed
CN-100528311-C Solvent composition ADEKA CORP (JP) 2009-08-19 CN disclosed
US-20090093588-A1 Solvent Composition ADEKA CORPORATION (JP) 2009-04-09 US disclosed
US-7507355-B2 Solvent composition ADEKA CORPORATION (JP) 2009-03-24 US disclosed
CN-101175554-A Solvent composition ADEKA CORP (JP) 2008-05-07 CN disclosed
US-20070257233-A1 Solvent Composition ADEKA CORPORATION (JP) 2007-11-08 US disclosed
CN-101048223-A Solvent composition ADEKA CORP (JP) 2007-10-03 CN disclosed
EP-1808223-A1 SOLVENT COMPOSITION Adeka Corporation (JP) 2007-07-18 EP disclosed
EP-1716577-A2 POLYMER SYSTEM WITH A CHARGE CARRIER MOBILITY THAT CAN BE ADJUSTED IN A DEFINED MANNER Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2006-11-02 EP disclosed
WO-2005078742-A2 POLYMER SYSTEM WITH A CHARGE CARRIER MOBILITY THAT CAN BE ADJUSTED IN A DEFINED MANNER Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2005-08-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190332023-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS SULT1E1, PSMB4, EPB41L2 GPR3 1533/4885TSHR 4502/4885CYP1A2 657/4885
US-20180057428-A1 Enhancing thermal stability of bulk heterojunction solar cells with fluorenone derivatives AXIN2, TRPA1, TCF4 GPR3 2137/4885TSHR 4086/4885CYP1A2 479/4885
US-10732526-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus SULT1E1, PSMB4, EPB41L2 GPR3 1533/4885TSHR 4502/4885CYP1A2 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.