Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045811 | 0.83 | CA1 (0.39) | CA1CA2ALOX15 | |
| SCHEMBL4598217 | 0.81 | CA1 (0.33) | CA1CA2ALOX15 | |
| SCHEMBL3426355 | 0.81 | SMN1; SMN2 (0.37) | DDAH1CA2 | |
| SCHEMBL11138013 | 0.79 | CA1 (0.45) | CA1CA2 | |
| SCHEMBL6395180 | 0.78 | — | — | |
| SCHEMBL7653761 | 0.76 | SMN1; SMN2 (0.34) | DDAH1CA2 | |
| SCHEMBL5830472 | 0.76 | SMN1; SMN2 (0.34) | DDAH1CA2 | |
| SCHEMBL4283577 | 0.75 | ALOX15 (0.34) | DDAH1ALOX15 | |
| SCHEMBL228308 | 0.75 | — | — | |
| SCHEMBL10702225 | 0.74 | DDAH1 (0.38) | DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871439-A4 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0871439-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024117-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |