Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098150 | 0.88 | ESR1 (0.47) | KMT2ALMNAL3MBTL1TDP1GAA | |
| SCHEMBL300994 | 0.88 | ESR1 (0.47) | KMT2ALMNAL3MBTL1TDP1GAA | |
| SCHEMBL1823023 | 0.88 | ESR1 (0.47) | KMT2ALMNAL3MBTL1TDP1GAA | |
| SCHEMBL2720024 | 0.87 | LMNA (0.38) | KMT2AMEN1LMNAL3MBTL1TDP1 | |
| SCHEMBL16673423 | 0.86 | MMP8 (0.51) | KMT2AMEN1LMNAL3MBTL1TDP1 | |
| SCHEMBL11307651 | 0.83 | MAPT (0.50) | LMNATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL3279844 | 0.78 | KMT2A (0.47) | KMT2AMEN1ACHELMNAAURKA | |
| SCHEMBL4068942 | 0.76 | MMP8 (0.54) | KMT2AMEN1ACHELMNAAURKA | |
| SCHEMBL3541681 | 0.76 | MEN1 (0.49) | KMT2AMEN1ACHELMNAL3MBTL1 | |
| SCHEMBL12310810 | 0.75 | ALDH1A1 (0.40) | KMT2AMEN1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163464-B2 | Propanoates and processes for preparing the same | Du Pont Electronic Polymers L.P. (US) | 2012-04-24 | — | — | US | disclosed |