Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098150 | 1.00 | ESR1 (0.47) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL1823023 | 1.00 | ESR1 (0.47) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL3426571 | 0.88 | KMT2A (0.43) | LMNAL3MBTL1KMT2ATDP1KDM4E | |
| SCHEMBL2720024 | 0.85 | LMNA (0.38) | LMNAL3MBTL1KMT2AOPRM1TDP1 | |
| SCHEMBL16673423 | 0.85 | MMP8 (0.51) | LMNAL3MBTL1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1823024 | 0.84 | ESR1 (0.38) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL11307651 | 0.81 | MAPT (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL2784263 | 0.79 | ESR1 (0.45) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL2783556 | 0.79 | ESR1 (0.45) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL9235662 | 0.79 | ESR1 (0.53) | ESR1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315739-B1 | NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME | DUPONT ELECTRONIC POLYMERS L P (US) | 2014-11-12 | — | — | EP | claimed |
| US-8163464-B2 | Propanoates and processes for preparing the same | Du Pont Electronic Polymers L.P. (US) | 2012-04-24 | — | — | US | claimed |
| JP-2012500846-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2315739-A1 | NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME | DuPont Electronic Polymers L.P. (US) | 2011-05-04 | — | — | EP | claimed |
| US-8163464-B2 | Propanoates and processes for preparing the same | Du Pont Electronic Polymers L.P. (US) | 2012-04-24 | — | — | US | disclosed |
| WO-2010024841-A1 | NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME | DUPONT ELECTRONIC POLYMERS L.P. (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20100047714-A1 | New propanoates and processes for preparing the same | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047714-A1 | New propanoates and processes for preparing the same | HPD, HMBS, LDHB | ESR1 1760/4885CA12 2635/4885CA1 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.