Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.51 |
| ▸ | MAX | P61244 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NAT1 | P18440 | 2/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427116 | 1.00 | MYC (0.51) | MYCMAXPDE4BPDE3ACISD1 | |
| SCHEMBL3427111 | 1.00 | MYC (0.51) | MYCMAXPDE4BPDE3ACISD1 | |
| SCHEMBL19425503 | 0.82 | PDE4B (0.69) | PDE4BPDE3ACISD1DYRK1AMEN1 | |
| SCHEMBL19420041 | 0.80 | MCL1 (0.53) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3422964 | 0.77 | KMO (0.52) | — | |
| SCHEMBL19425343 | 0.77 | MCL1 (0.58) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3425202 | 0.77 | MCL1 (0.62) | MEN1KMT2AALDH1A1MAPTADAMTS5 | |
| SCHEMBL3422932 | 0.75 | MCL1 (0.56) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3422944 | 0.75 | MCL1 (0.56) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3422938 | 0.75 | MCL1 (0.56) | GAAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024783-A1 | BIARYLRHODANINE AND PYRIDYLRHODANINE COMPOUNDS AND THEIR USE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-03-04 | — | — | WO | disclosed |