Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.70 |
| ▸ | HTR3A | P46098 | 17/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863534 | 0.86 | HTR1A (0.73) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6531046 | 0.85 | HTR1A (0.53) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27846478 | 0.82 | HTR1A (0.50) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14734867 | 0.82 | HTR1A (1.00) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6531051 | 0.79 | HTR1A (0.71) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15856950 | 0.77 | HTR1A (0.59) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17752147 | 0.76 | HTR1A (0.57) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6531047 | 0.75 | GAA (0.46) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27934132 | 0.75 | MAPK1 (0.74) | KEAP1MAPK1 | |
| SCHEMBL30100764 | 0.75 | GAA (0.48) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959859-B | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2013-08-14 | — | — | CN | disclosed |
| CN-101959859-B | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2013-08-14 | — | — | CN | disclosed |
| CN-101959859-B | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2013-08-14 | — | — | CN | disclosed |
| US-8362255-B2 | Process for the manufacture of [phenylsulfanylphenyl]piperidines | H. LUNDBECK A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| US-8362255-B2 | Process for the manufacture of [phenylsulfanylphenyl]piperidines | H. LUNDBECK A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| US-8362255-B2 | Process for the manufacture of [phenylsulfanylphenyl]piperidines | H. LUNDBECK A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| EP-2260024-B1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | LUNDBECK & CO AS H (DK) | 2011-12-28 | — | — | EP | disclosed |
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2011-03-03 | — | — | US | disclosed |
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2011-03-03 | — | — | US | disclosed |
| CN-101959859-A | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2011-01-26 | — | — | CN | disclosed |
| CN-101959859-A | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2011-01-26 | — | — | CN | disclosed |
| CN-101959859-A | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2011-01-26 | — | — | CN | disclosed |
| EP-2260024-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | H. Lundbeck A/S (DK) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260024-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | H. Lundbeck A/S (DK) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009109541-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109541-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2009-09-11 | — | — | WO | disclosed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | NPEPPS, UMPS, DHPS | HTR1A 1380/4885HTR3A 1417/4885CYP1A2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.