Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.53 |
| ▸ | HTR3A | P46098 | 14/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428277 | 0.85 | HTR1A (0.70) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27863534 | 0.79 | HTR1A (0.73) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6531047 | 0.78 | GAA (0.46) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26253981 | 0.75 | SIRT1 (0.50) | HTR1AHTR3ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27846478 | 0.73 | HTR1A (0.50) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6531051 | 0.72 | HTR1A (0.71) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30228454 | 0.72 | LMNA (0.68) | GAAMEN1LMNAKMT2AMAPK1 | |
| SCHEMBL9065218 | 0.72 | LMNA (0.68) | GAAMEN1LMNAKMT2AMAPK1 | |
| SCHEMBL8894088 | 0.72 | LMNA (0.68) | GAAMEN1LMNAKMT2AMAPK1 | |
| SCHEMBL6105727 | 0.71 | NPC1 (0.54) | GAAMEN1LMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362255-B2 | Process for the manufacture of [phenylsulfanylphenyl]piperidines | H. LUNDBECK A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| EP-2260024-B1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | LUNDBECK & CO AS H (DK) | 2011-12-28 | — | — | EP | disclosed |
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | NPEPPS, UMPS, DHPS | HTR1A 1380/4885HTR3A 1417/4885CYP1A2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.