Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11164151 | 0.97 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Phenanthrene SCHEMBL28440108 | 0.86 | HSD17B10 (0.67) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL18979413 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL11693494 | 0.79 | CYP2A6 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Phenanthrene SCHEMBL29358486 | 0.77 | CYP2A6 (1.00) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Phenanthrene SCHEMBL29477074 | 0.77 | CYP2A6 (1.00) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Phenanthrene SCHEMBL7643 | 0.77 | CYP2A6 (1.00) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Phenanthrene SCHEMBL30932938 | 0.77 | CYP2A6 (1.00) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL4377802 | 0.77 | ALDH1A1 (0.85) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Phenanthrene SCHEMBL27458043 | 0.77 | CYP2A6 (1.00) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035360-B1 | 5,6,8,9-TETRAHYDRO-7H-DIBENZ(D,F)AZONINE DERIVATIVES, THE PRODUCTION THEREOF AND COMPOSITIONS CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1983-09-21 | — | — | EP | claimed |
| WO-2016149821-A1 | METHODS OF MAKING MORPHINAN ALKALOIDS AND ENZYMES THEREFORE | Valorbec Société en Commandite (CA) | 2016-09-29 | — | — | WO | disclosed |
| US-7767428-B2 | Salutaridinol 7-O-acetyltransferase and derivatives thereof | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090053764-A1 | Salutaridinol 7-0-Acetyltransferase and Derivatives Thereof | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2009-02-26 | — | — | US | disclosed |
| US-7390642-B2 | Salutaridinol 7-O-acetyltransferase and derivatives thereof | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2008-06-24 | — | — | US | disclosed |
| US-20030226161-A1 | Salutaridinol 7-O-acetyltransferase and derivatives thereof | DONALD DANFORTH PLANT SCIENCE CENTER | 2003-12-04 | — | — | US | disclosed |
| EP-1270727-A1 | Salutaridinol 7-O-acetyltransferase and derivatives thereof | Institut für Pflanzenbiochemie (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-0035360-B1 | 5,6,8,9-TETRAHYDRO-7H-DIBENZ(D,F)AZONINE DERIVATIVES, THE PRODUCTION THEREOF AND COMPOSITIONS CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1983-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053764-A1 | Salutaridinol 7-0-Acetyltransferase and Derivatives Thereof | NAT10, RNGTT, RNMT | ALDH1A1 1203/4885HSD17B10 899/4885CYP2A6 2473/4885 |
| US-20030226161-A1 | Salutaridinol 7-O-acetyltransferase and derivatives thereof | NAT10, RNGTT, METTL16 | ALDH1A1 1143/4885HSD17B10 596/4885CYP2A6 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.