SCHEMBL342990

SCHEMBL342990

CN(C)CCC(NC(CCN(C)C)c1ccccn1)c1ccccn1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 5/20 0.62
SLC6A2 P23975 5/20 0.62
SLC6A4 P31645 5/20 0.62
SCN1A P35498 3/20 0.62
SCN2A Q99250 3/20 0.62
SCN3A Q9NY46 3/20 0.62
KCNH2 Q12809 5/20 0.55
CHRM1 P11229 4/20 0.55
HRH1 P35367 4/20 0.55
SLC6A3 Q01959 4/20 0.55
HRH3 Q9Y5N1 4/20 0.55
ADRA2B P18089 3/20 0.55
HTR2A P28223 3/20 0.55
TSHR P16473 3/20 0.55
LMNA P02545 3/20 0.55
CYP2D6 P10635 2/20 0.55
NFKB1 P19838 2/20 0.55
THPO P40225 2/20 0.55
DRD1 P21728 2/20 0.55
HTR2C P28335 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19381942 0.79 CHRM2 (0.66) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL343645 0.77 HRH1 (0.41) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL4796 0.77 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL30182646 0.77 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL126153 0.77 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL19368168 0.77 CHRM2 (0.62) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL48720 0.77 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL365145 0.75 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SCN1ASCN2A
Pheniramine SCHEMBL18240052 0.75 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL18157956 0.73 CHRM2 (0.47) CHRM2SLC6A2SLC6A4SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338600-B2 Copper-oxygen adduct complexes, and methods of making and use JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2012-12-25 US claimed
EP-2215096-B1 COPPER-OXYGEN ADDUCT COMPLEXES UNIV GIESSEN JUSTUS LIEBIG (DE) 2012-09-19 EP claimed
US-20120016127-A1 COPPER-OXYGEN ADDUCT COMPLEXES JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2012-01-19 US claimed
EP-2215096-A1 COPPER-OXYGEN ADDUCT COMPLEXES Justus-Liebig-Universität Gießen (DE) 2010-08-11 EP claimed
WO-2009052809-A1 COPPER-OXYGEN ADDUCT COMPLEXES JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2009-04-30 WO claimed
US-8338600-B2 Copper-oxygen adduct complexes, and methods of making and use JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2012-12-25 US disclosed
EP-2215096-B1 COPPER-OXYGEN ADDUCT COMPLEXES UNIV GIESSEN JUSTUS LIEBIG (DE) 2012-09-19 EP disclosed
US-20120016127-A1 COPPER-OXYGEN ADDUCT COMPLEXES JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2012-01-19 US disclosed
EP-2215096-A1 COPPER-OXYGEN ADDUCT COMPLEXES Justus-Liebig-Universität Gießen (DE) 2010-08-11 EP disclosed
WO-2009052809-A1 COPPER-OXYGEN ADDUCT COMPLEXES JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2009-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016127-A1 COPPER-OXYGEN ADDUCT COMPLEXES AOC2, AOC3, AOC1 CHRM2 2513/4885SLC6A2 1140/4885SLC6A4 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.