Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 8/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575534 | 0.85 | ESR1 (0.39) | GLAESR1IDH1KDM4EMAPT | |
| SCHEMBL9061566 | 0.77 | ESR1 (0.55) | ESR1HRH4IDH1 | |
| SCHEMBL10862760 | 0.77 | CA1 (0.37) | NPC1RAB9ATP53GLAMAPK1 | |
| SCHEMBL11396440 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8379029 | 0.74 | NPC1 (0.31) | NPC1RAB9ATP53GLAMAPK1 | |
| SCHEMBL8463123 | 0.73 | ESR1 (0.38) | SMN1; SMN2CA1CA2CA9ESR1 | |
| SCHEMBL545236 | 0.72 | CA1 (0.37) | NPC1RAB9ATP53GLAMAPK1 | |
| Formaldehyde SCHEMBL11354570 | 0.72 | ESR1 (0.50) | CA1CA2CA9ESR1HRH4 | |
| SCHEMBL8426213 | 0.72 | HTR7 (0.38) | CA1CA2CA9ESR1HTR7 | |
| SCHEMBL25245215 | 0.71 | CA1 (0.36) | NPC1RAB9ATP53GLAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2249959-B1 | PRODUCT | GIVAUDAN SA (CH) | 2016-04-13 | — | — | EP | disclosed |
| US-8357651-B2 | Aminoplast microcapsules containing fragrance | GIVAUDAN SA (CH) | 2013-01-22 | — | — | US | disclosed |
| US-20100323938-A1 | Product | GIVAUDAN SA (CH) | 2010-12-23 | — | — | US | disclosed |
| EP-2249959-A1 | PRODUCT | Givaudan SA (CH) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100553-A1 | PRODUCT | GIVAUDAN SA (CH) | 2009-08-20 | — | — | WO | disclosed |
| EP-1065227-B1 | Color improvement of dimethoxyethanal-melamine resins | CLARIANT FRANCE SA (FR) | 2004-09-01 | — | — | EP | disclosed |
| EP-1065227-A3 | Color improvement of dimethoxyethanal-melamine resins | Clariant (France) S.A. (FR) | 2002-07-31 | — | — | EP | disclosed |
| EP-1065227-A2 | Color improvement of dimethoxyethanal-melamine resins | Clariant (France) S.A. (FR) | 2001-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323938-A1 | Product | SRM, PNMT, PFAS | NPC1 4680/4885RAB9A 4121/4885TP53 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.