Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430044 | 0.86 | FFAR1 (0.48) | FFAR1FFAR4DHODHMGLLMME | |
| SCHEMBL3431483 | 0.79 | FFAR1 (0.43) | FFAR1FFAR4DHODHMGLLMME | |
| SCHEMBL3430623 | 0.76 | FFAR1 (0.43) | FFAR1FFAR4DHODHHPGDHTT | |
| SCHEMBL3347691 | 0.76 | FFAR4 (0.40) | FFAR1FFAR4DHODHGRIN1GRIN2B | |
| SCHEMBL3353013 | 0.75 | DHODH (0.45) | FFAR1FFAR4DHODHMGLLSLC13A5 | |
| SCHEMBL3346002 | 0.75 | GRIN2D (0.41) | FFAR1FFAR4DHODHGRIN1GRIN2B | |
| SCHEMBL3352922 | 0.73 | GSK3B (0.38) | FFAR1FFAR4DHODHPIM1PIM2 | |
| SCHEMBL3346086 | 0.72 | PTGER4 (0.44) | DHODHGRIN1GRIN2B | |
| SCHEMBL3346362 | 0.71 | DHODH (0.39) | DHODHXDHHDAC6GRIN1GRIN2B | |
| SCHEMBL3430136 | 0.70 | DHODH (0.39) | DHODHHPGDXDHHDAC6GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |