SCHEMBL3430857

SCHEMBL3430857

C1=Nc2ccccc2C12C[N]2

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL29199293 0.71
SCHEMBL30068180 0.71 ADORA3 (0.34) ADORA3
SCHEMBL9364337 0.71 ADORA3 (0.34) ADORA3
SCHEMBL28886117 0.68
SCHEMBL29639106 0.68 HTR5A (0.35)
SCHEMBL27940478 0.68 HTR5A (0.31)
SCHEMBL30876182 0.68
SCHEMBL926937 0.68 HTR5A (0.35)
SCHEMBL5851114 0.68 ADORA3 (0.35) ADORA3
SCHEMBL21834171 0.68 ADORA3 (0.36) ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2265620-A1 SPIRO DERIVATIVES OF PARTHENIN AS NOVEL ANTICANCER AGENTS Council Of Scientific & Industrial Research (IN) 2010-12-29 EP disclosed
WO-2009110007-A1 SPIRO DERIVATIVES OF PARTHENIN AS NOVEL ANTICANCER AGENTS COUNCIL QF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2009-09-11 WO disclosed