Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907993 | 1.00 | ACP3 (0.47) | ACP3P2RX7PDE2ACNR2HSD11B1 | |
| SCHEMBL29580255 | 1.00 | ACP3 (0.47) | ACP3P2RX7PDE2ACNR2HSD11B1 | |
| SCHEMBL1047627 | 1.00 | ACP3 (0.47) | ACP3P2RX7PDE2ACNR2HSD11B1 | |
| SCHEMBL13168657 | 1.00 | ACP3 (0.47) | ACP3P2RX7PDE2ACNR2HSD11B1 | |
| SCHEMBL2986939 | 1.00 | ACP3 (0.47) | ACP3P2RX7PDE2ACNR2HSD11B1 | |
| Phthalic Acid SCHEMBL3626025 | 0.86 | TAS2R14 (0.48) | ACP3P2RX7CNR2ALDH1A1LMNA | |
| Phthalic Acid SCHEMBL3626023 | 0.86 | TAS2R14 (0.48) | ACP3P2RX7CNR2ALDH1A1LMNA | |
| SCHEMBL8539373 | 0.83 | ACP3 (0.49) | ACP3P2RX7PDE2ACNR2HSD11B1 | |
| SCHEMBL84477 | 0.82 | P2RX7 (0.50) | ACP3P2RX7CNR2HSD11B1SMN1; SMN2 | |
| SCHEMBL9776265 | 0.82 | ACP3 (0.50) | ACP3P2RX7CNR2ALDH1A1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107118986-B | Pseudomonas putida and application thereof in preparation of (R) -1- (2-trifluoromethylphenyl) ethanol | 浙江医药高等专科学校 | 2020-08-11 | — | — | CN | claimed |
| CN-107746861-B | Biological preparation method of (R) -1- (2-trifluoromethylphenyl) ethanol | 浙江工业大学 | 2020-06-23 | — | — | CN | claimed |
| US-20230250093-A1 | AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-08-10 | — | — | US | disclosed |
| US-20230212149-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20230212149-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-11548871-B2 | Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| CN-112176019-B | Method for preparing (R) -1- (3-trifluoromethylphenyl) ethanol by biological catalysis | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| US-20210171500-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2021-06-10 | — | — | US | disclosed |
| CN-112176019-A | Method for preparing (R) -1- (3-trifluoromethylphenyl) ethanol by biological catalysis | 浙江工业大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-107118986-B | Pseudomonas putida and application thereof in preparation of (R) -1- (2-trifluoromethylphenyl) ethanol | 浙江医药高等专科学校 | 2020-08-11 | — | — | CN | disclosed |
| CN-107118986-B | Pseudomonas putida and application thereof in preparation of (R) -1- (2-trifluoromethylphenyl) ethanol | 浙江医药高等专科学校 | 2020-08-11 | — | — | CN | disclosed |
| US-20110054223-A1 | Method for Purifying Optically Active 1-(2-Trifluoromethylphenyl)Ethanol | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141761-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100311799-A1 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| EP-2248795-A1 | METHOD FOR PURIFYING OPTICALLY ACTIVE 1-(2-TRIFLUOROMETHYLPHENYL)ETHANOL | Central Glass Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100278833-A1 | THIOPHENE-IMIDAZOPYRIDINES | 4SC AG (DE) | 2010-11-04 | — | — | US | disclosed |
| WO-2009003911-A1 | THIOPHENE-IMIDAZOPYRIDINES | 4SC AG (DE) | 2009-01-08 | — | — | WO | disclosed |
| EP-1935866-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL | Central Glass Company, Limited (JP) | 2008-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054223-A1 | Method for Purifying Optically Active 1-(2-Trifluoromethylphenyl)Ethanol | ADH1C, ADH1A, ADH5 | ACP3 1689/4885P2RX7 4800/4885PDE2A 4319/4885 |
| US-11548871-B2 | Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof | LPAR3, LPAR1, LPAR2 | ACP3 250/4885P2RX7 526/4885PDE2A 1086/4885 |
| US-20100278833-A1 | THIOPHENE-IMIDAZOPYRIDINES | PIKFYVE, PIP4K2B, PIP5K1B | ACP3 2400/4885P2RX7 3076/4885PDE2A 1586/4885 |
| US-20230250093-A1 | AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | LPAR1, LPAR2, LPAR3 | ACP3 1383/4885P2RX7 757/4885PDE2A 1172/4885 |
| US-20210171500-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | LPAR3, LPAR1, LPAR2 | ACP3 250/4885P2RX7 526/4885PDE2A 1086/4885 |
| US-20230212149-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | LPAR3, LPAR1, LPAR2 | ACP3 250/4885P2RX7 526/4885PDE2A 1086/4885 |
| US-20100311799-A1 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | LPAR1, LPAR2, LPAR4 | ACP3 657/4885P2RX7 137/4885PDE2A 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.