SCHEMBL3432839

SCHEMBL3432839

Nc1cccc(-c2nc3nc(-c4cccc(N)c4)sc3s2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.58
▸ ALDH1A1 P00352 5/20 0.58
▸ MAPT P10636 5/20 0.58
▸ MEN1 O00255 5/20 0.58
▸ NPC1 O15118 4/20 0.58
▸ KMT2A Q03164 4/20 0.58
▸ HPGD P15428 4/20 0.58
▸ RAB9A P51151 3/20 0.58
▸ GLA P06280 3/20 0.58
▸ GAA P10253 2/20 0.58
▸ PKM P14618 2/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ CASP1 P29466 2/20 0.58
▸ NFKB1 P19838 1/20 0.58
▸ NFKB2 Q00653 1/20 0.58
▸ RELA Q04206 1/20 0.58
▸ TP53 P04637 1/20 0.58
▸ POLB P06746 1/20 0.58
▸ PTBP1 P26599 1/20 0.58
▸ CASP7 P55210 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13470771 0.77 NPC1 (0.61) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL7636568 0.76 HSD17B1 (0.59) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL11436304 0.76 APP (0.52) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL1091789 0.75 ALDH1A1 (0.55) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL11749206 0.74 MAPT (1.00) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL2242693 0.74 RAB9A (1.00) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL6401979 0.74 MAPT (0.77) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL30776283 0.74 RAB9A (1.00) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL11656487 0.73 MAPT (0.74) KDM4EALDH1A1MAPTMEN1NPC1
SCHEMBL6396202 0.73 MAPT (0.65) KDM4EALDH1A1MAPTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 — — US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 — — US claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 — — US claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 — — US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 — — US claimed
US-10774216-B2 Resin composition and uses of the same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2020-09-15 — — US disclosed
US-10513607-B2 Resin composition and uses of the same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2019-12-24 — — US disclosed
US-20190144666-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2019-05-16 — — US disclosed
US-20180030267-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2018-02-01 — — US disclosed
US-20170260365-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2017-09-14 — — US disclosed
EP-2209156-A1 Composite membrane and method for making General Electric Company (US) 2010-07-21 — — EP disclosed
US-20100167100-A1 COMPOSITE MEMBRANE AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY 2010-07-01 — — US disclosed
US-4038450-A STORAGE STABILITY RHONE-POULENC S.A. (FR) 1977-07-26 — — US disclosed
US-4013600-A STORAGE STABILITY RHONE-POULENC INDUSTRIES (FR) 1977-03-22 — — US disclosed
US-4012361-A Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine RHONE-POULENC S.A. (FR) 1977-03-15 — — US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 — — US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 — — US disclosed
US-3970714-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-07-20 — — US disclosed
US-3966678-A Maleic anhydride-polyaldimine prepolymers RHONE-POULENC S.A. (FR) 1976-06-29 — — US disclosed
US-3933745-A Imide copolymers possessing hydroxyl groups RHONE-POULENC S.A. (FR) 1976-01-20 — — US disclosed
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