SCHEMBL3432895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21883003	0.91	MAPT (0.36)	LMNAALDH1A1ACHEMAPK1BLM
	SCHEMBL238708	0.89	HDAC3 (0.39)	LMNAACHETSHRCYP2C19RAB9A
	SCHEMBL18910149	0.85	TSHR (0.39)	ESRRGLMNAALDH1A1ACHEMAPK1
	SCHEMBL3421885	0.83	HDAC3 (0.38)	LMNAACHEMAPK1BLMPMP22
	SCHEMBL3428114	0.83	RIPK1 (0.42)	LMNAALDH1A1EPHX2RAB9ANPC1
	SCHEMBL13342972	0.82	MLYCD (0.37)	LMNAALDH1A1ACHEMAPK1BLM
	SCHEMBL3433517	0.82	LMNA (0.39)	LMNAALDH1A1ACHEMAPK1BLM
	SCHEMBL3221660	0.81	LMNA (0.34)	LMNAALDH1A1ACHEMAPK1BLM
	SCHEMBL3424355	0.81	RORC (0.40)	LMNAACHETSHRCYP2C19RAB9A
	SCHEMBL8174827	0.77	HDAC3 (0.37)	LMNAACHEMAPK1BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.