SCHEMBL992041

SCHEMBL992041

O=C(O)CCc1nccs1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.44
HDAC6 Q9UBN7 2/20 0.43
PLA2G4A P47712 1/20 0.41
FFAR1 O14842 1/20 0.40
COPS5 Q92905 1/20 0.40
CES1 P23141 1/20 0.40
ALDH1A1 P00352 2/20 0.39
SLC6A3 Q01959 1/20 0.39
MCL1 Q07820 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KEAP1 Q14145 1/20 0.38
TSHR P16473 1/20 0.37
P4HTM Q9NXG6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL6283872 0.90 TRPM8 (0.48) FFAR1ALDH1A1SLC6A3KDM4EMAPT
SCHEMBL6179956 0.89 SMN1; SMN2 (0.44) FDPSHDAC6PLA2G4AFFAR1COPS5
O-Xylene SCHEMBL6283877 0.87 PLA2G4A (0.43) PLA2G4AFFAR1COPS5CES1ALDH1A1
SCHEMBL11156307 0.87 PLA2G4A (0.48) PLA2G4ACES1MAPT
SCHEMBL28011812 0.86 FDPS (0.46) FDPSPLA2G4ACOPS5CES1ALDH1A1
SCHEMBL7174088 0.85 CES1 (0.49) PLA2G4ACES1MAPTHPGD
SCHEMBL175216 0.82 FDPS (0.43) FDPSPLA2G4ACOPS5CES1ALDH1A1
SCHEMBL4574427 0.82 ALDH1A1 (0.47) FDPSPLA2G4ACOPS5CES1ALDH1A1
SCHEMBL14257698 0.82 FDPS (0.43) FDPSPLA2G4ACOPS5CES1ALDH1A1
Hydrochloric Acid SCHEMBL31146299 0.81 FDPS (0.42) FDPSPLA2G4ACOPS5CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118591200-A Surface modification layer, trans-perovskite battery and preparation method of trans-perovskite battery 四川恒立聚能光电科技有限公司 2024-09-03 CN claimed
EP-2456781-B1 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ACYLOXYALKYLENE PHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES BAYER IP GMBH (DE) 2017-06-21 EP claimed
US-9096639-B2 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene phenyl derivatives, methods for the production thereof and use thereof for treating diseases BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-08-04 US claimed
US-20120232042-A1 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ACYLOXYALKYLENE PHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-09-13 US claimed
EP-2456781-A2 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ACYLOXYALKYLENE PHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES Bayer Pharma Aktiengesellschaft (DE) 2012-05-30 EP claimed
WO-2011009530-A2 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ACYLOXYALKYLENE PHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-01-27 WO claimed
EP-1926719-A2 2-ANILINE-4-ARYL SUBSTITUTED THIAZOLE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2008-06-04 EP claimed
WO-2007031440-A2 2-ANILINE-4-ARYL SUBSTITUTED THIAZOLE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-22 WO claimed
WO-2005115148-A1 3-ARYL-3-HYDROXY-2-METHYLENEPROPIONIC ACID ESTERS AS FUNGICIDES CROPSOLUTION, INC. (US) 2005-12-08 WO claimed
EP-0021688-B1 7-(THIAZOLYLPROPIONAMIDO) CEPHALOSPORINS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-07-13 EP claimed
EP-4029868-B1 MCL-1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-20 EP disclosed
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
EP-3882252-B1 BETA-LACTAMASE INHIBITORS VENATORX PHARMACEUTICALS INC (US) 2025-11-19 EP disclosed
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS AGIOS PHARMACEUTICALS INC (US) 2025-10-16 US disclosed
EP-0486948-A2 Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1992-05-27 EP disclosed
US-4581353-A ANTIBIOTIC, BACTERICIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-04-08 US disclosed
EP-0021688-B1 7-(THIAZOLYLPROPIONAMIDO) CEPHALOSPORINS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-07-13 EP disclosed
EP-0021688-A1 7-(Thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1981-01-07 EP disclosed
EP-0021688-A1 7-(Thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 FDPS 2285/4885HDAC6 344/4885PLA2G4A 3474/4885
US-20120232042-A1 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ACYLOXYALKYLENE PHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES CYP19A1, HSD17B11, SHBG FDPS 730/4885HDAC6 3658/4885PLA2G4A 1646/4885
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto HTR2C, HTR1A, HTR2A FDPS 3584/4885HDAC6 2254/4885PLA2G4A 1560/4885
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS PAH, KDM8, PHF8 FDPS 656/4885HDAC6 3096/4885PLA2G4A 3341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.