Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CPT2 | P23786 | 1/20 | 0.50 |
| ▸ | CPT1A | P50416 | 1/20 | 0.50 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849755 | 0.94 | PKM (0.59) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL19844153 | 0.93 | L3MBTL1 (0.51) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL10597694 | 0.85 | KDM4E (0.65) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL27691343 | 0.84 | HRH3 (0.64) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL21422363 | 0.82 | KDM4E (0.61) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL29045152 | 0.82 | KDM4E (0.61) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL3434811 | 0.82 | PKM (0.59) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL3434351 | 0.81 | RAB9A (0.69) | TDP1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL22146533 | 0.81 | TDP1 (0.66) | TDP1KDM4EMAPK1MAPTMEN1 | |
| SCHEMBL14579705 | 0.81 | L3MBTL1 (0.51) | TDP1MAPK1MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957223-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957223-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | FIRST NATIONAL BANK OF PENNSYLVANIA | 2018-02-08 | — | — | US | disclosed |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | FIRST NATIONAL BANK OF PENNSYLVANIA | 2018-02-08 | — | — | US | disclosed |
| US-9409852-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC (US) | 2016-08-09 | — | — | US | disclosed |
| US-9409852-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC (US) | 2016-08-09 | — | — | US | disclosed |
| US-20140031578-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | ETHOX CHEMICALS, LLC | 2014-01-30 | — | — | US | disclosed |
| US-20140031578-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | ETHOX CHEMICALS, LLC | 2014-01-30 | — | — | US | disclosed |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC | 2012-04-26 | — | — | US | disclosed |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031578-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | AHR, AR, ARNT | TDP1 4722/4885KDM4E 1017/4885MAPK1 4628/4885 |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | AHR, AR, ARNT | TDP1 4713/4885KDM4E 1009/4885MAPK1 4641/4885 |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | AHR, AR, ARNT | TDP1 4713/4885KDM4E 1009/4885MAPK1 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.