Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433438 | 1.00 | CNR2 (0.45) | CNR2CNR1NR4A2PARGLMNA | |
| SCHEMBL944734 | 0.85 | GPR84 (0.48) | LMNAOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL947139 | 0.81 | SLC6A4 (0.45) | CNR2CNR1PARGOPRM1OPRK1 | |
| SCHEMBL945731 | 0.77 | CNR2 (0.40) | CNR2CNR1NR4A2PARGCCNT1 | |
| SCHEMBL3433332 | 0.77 | CNR2 (0.40) | CNR2CNR1NR4A2PARGCCNT1 | |
| SCHEMBL3434033 | 0.75 | HTR1A (0.37) | PARG | |
| SCHEMBL21614275 | 0.68 | NR4A2 (0.52) | CNR2CNR1NR4A2ICMTCCNT1 | |
| SCHEMBL1176855 | 0.67 | POLB (0.54) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL2333756 | 0.67 | POLB (0.54) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL5408210 | 0.67 | POLB (0.54) | OPRM1OPRK1OGFRL1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146351-A1 | INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-12-23 | — | — | WO | disclosed |