Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519421 | 1.00 | POLB (0.64) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL9614337 | 0.86 | POLB (0.60) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL3433644 | 0.84 | IMPDH2 (0.59) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL30678031 | 0.84 | IMPDH2 (0.59) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL10345038 | 0.82 | ALDH1A1 (0.74) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL4219929 | 0.78 | ALDH1A1 (0.61) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL9709372 | 0.78 | ALDH1A1 (0.61) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL1613016 | 0.78 | PARP1 (0.57) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL11981333 | 0.78 | POLB (1.00) | POLBTDP1ALDH1A1KDM4EGAA | |
| SCHEMBL31714622 | 0.78 | ALDH1A1 (0.61) | POLBTDP1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101218307-B | Pigment dispersions with poymeric dispersants having pending chromophore groups | AGFA GEVAERT | 2012-03-28 | — | — | CN | disclosed |
| US-7846939-B2 | Salts and mixture of 9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols, pharmaceutical compositions containing said agents and treatment methods | EPHAG AS (EE) | 2010-12-07 | — | — | US | disclosed |
| US-20100144780-A1 | Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods | PJSC PHARMSYNTHEZ (RU) | 2010-06-10 | — | — | US | disclosed |
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144780-A1 | Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods | ADSL, ACMSD, ASS1 | POLB 776/4885TDP1 529/4885ALDH1A1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.