⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421110 | 0.88 | MAPK14 (0.34) | — | |
| SCHEMBL5226655 | 0.80 | SLC2A1 (0.40) | — | |
| SCHEMBL3434367 | 0.71 | JAK2 (0.35) | — | |
| SCHEMBL1640422 | 0.70 | CAMK2D (0.42) | — | |
| SCHEMBL13816258 | 0.69 | RORB (0.33) | — | |
| SCHEMBL1641900 | 0.68 | MAPT (0.47) | — | |
| SCHEMBL3434765 | 0.67 | ALDH1A2 (0.32) | — | |
| SCHEMBL1641438 | 0.67 | GPBAR1 (0.39) | — | |
| SCHEMBL1641885 | 0.66 | PDE4D (0.48) | — | |
| SCHEMBL1642023 | 0.66 | LCLAT1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231625-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076140-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |