Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223915 | 0.76 | MAPK14 (0.34) | — | |
| SCHEMBL3434769 | 0.74 | BRAF (0.35) | ALDH1A2BRAF | |
| SCHEMBL3421110 | 0.73 | MAPK14 (0.34) | BRAF | |
| SCHEMBL1641680 | 0.72 | BRAF (0.49) | ALDH1A2BRAF | |
| SCHEMBL2193407 | 0.67 | BRAF (0.61) | BRAF | |
| SCHEMBL3434366 | 0.67 | — | — | |
| SCHEMBL9989084 | 0.65 | BRAF (0.55) | BRAF | |
| SCHEMBL1640122 | 0.65 | TGFBR1 (0.41) | BRAF | |
| SCHEMBL2254385 | 0.64 | CYP1A1 (0.46) | — | |
| SCHEMBL3421116 | 0.64 | MAPK14 (0.37) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231625-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076140-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |