Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276275 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL211474 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL244752 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL6985283 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8114168 | 0.76 | ALDH1A1 (0.71) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6239673 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL179966 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL304332 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL23372773 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL27655315 | 0.73 | ALDH1A1 (0.62) | ALDH1A1MAPTCYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146351-A1 | INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-12-23 | — | — | WO | disclosed |