Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532768 | 0.86 | MAPT (0.56) | MAPTTSHRHTTKMT2AMEN1 | |
| SCHEMBL6327123 | 0.86 | MAPT (0.49) | MAPTTSHRHTTKMOKMT2A | |
| SCHEMBL10559130 | 0.84 | HTT (0.48) | MAPTHTTKMT2AMEN1NPC1 | |
| SCHEMBL11581875 | 0.83 | MAPT (0.50) | MAPTHTTKMT2AMEN1KDM4E | |
| SCHEMBL5685428 | 0.82 | MAPT (0.56) | MAPTTSHRHTTSRD5A2KMT2A | |
| SCHEMBL9681845 | 0.82 | MAPT (0.49) | MAPTTSHRHTTKMOSRD5A2 | |
| SCHEMBL9681852 | 0.82 | MAPT (0.52) | MAPTTSHRHTTKMT2AMEN1 | |
| SCHEMBL11797978 | 0.81 | KMO (0.44) | MAPTTSHRKMOKMT2AMEN1 | |
| SCHEMBL10893735 | 0.80 | KDM4E (0.49) | MAPTHTTKMT2AMEN1KDM4E | |
| SCHEMBL10892778 | 0.80 | ALDH1A1 (0.46) | MAPTHTTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257530-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | Bayer CropScience Aktiengesellschaft (DE) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106234-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | WO | disclosed |