SCHEMBL343571

SCHEMBL343571

CCCc1ccc(OC(=O)CN)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.60
KMT2A Q03164 5/20 0.51
PLA2G1B P04054 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 1/20 0.48
CASP3 P42574 1/20 0.48
RAB9A P51151 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
ALDH1A1 P00352 2/20 0.46
THRA P10827 1/20 0.45
ESR1 P03372 1/20 0.43
RECQL P46063 1/20 0.43
HIF1A Q16665 1/20 0.43
PLK1 P53350 1/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27316983 0.90 THRB (0.56) THRBSMN1; SMN2ALDH1A1THRAPLK1
SCHEMBL20593516 0.85 THRB (0.64) THRBKMT2APLA2G1BATG4BSMN1; SMN2
SCHEMBL14416710 0.85 RAB9A (0.50) THRBKMT2ASMN1; SMN2MAPTNPC1
SCHEMBL10694275 0.85 THRB (0.64) THRBKMT2APLA2G1BATG4BSMN1; SMN2
SCHEMBL18274704 0.85 TAAR1 (0.52) THRBKMT2AALDH1A1L3MBTL1
SCHEMBL1839411 0.81 THRB (0.64) THRBKMT2APLA2G1BATG4BSMN1; SMN2
SCHEMBL234883 0.81 THRB (0.68) THRBKMT2APLA2G1BATG4BSMN1; SMN2
SCHEMBL7065317 0.81 THRB (0.68) THRBKMT2APLA2G1BATG4BSMN1; SMN2
SCHEMBL3899589 0.79 THRB (0.66) THRBKMT2APLA2G1BATG4BSMN1; SMN2
SCHEMBL9642421 0.79 THRB (0.66) THRBKMT2APLA2G1BATG4BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
EP-4602141-A1 A FRAGRANCE MIXTURE (VI) Symrise AG (DE) 2025-08-20 EP claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
EP-4519403-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-03-12 EP claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
EP-4473079-A1 A FRAGRANCE MIXTURE Symrise AG (DE) 2024-12-11 EP claimed
US-20240358611-A1 COMPOSITIONS SYMRISE AG (DE) 2024-10-31 US claimed
EP-4429465-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS Symrise AG (DE) 2024-09-18 EP claimed
EP-4387587-A1 COMPOSITIONS Symrise AG (DE) 2024-06-26 EP claimed
WO-2023213386-A1 A FRAGRANCE MIXTURE (V) SYMRISE AG (DE) 2023-11-09 WO claimed
WO-2023147852-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2023-08-10 WO claimed
WO-2023147874-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2023-08-10 WO claimed
WO-2023083445-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS SYMRISE AG (DE) 2023-05-19 WO claimed
WO-2023021012-A1 COMPOSITIONS SYMRISE AG (DE) 2023-02-23 WO claimed
US-11344857-B2 Microcapsules SYMRISE AG (DE) 2022-05-31 US claimed
US-11116712-B2 Fragrance composition SYMRISE AG (DE) 2021-09-14 US claimed
EP-1660621-B1 AGENTS THAT ARE ABSORBED BY THE SURFACE OF SUBSTRATES HENKEL AG & CO KGAA (DE) 2012-02-01 EP claimed
US-7446086-B2 Agents that are absorbed on the surfaces of substrates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-11-04 US claimed
US-20060229230-A1 Agents that are absorbed on the surfaces of substrates HENKEL AG & CO. KGAA (DE) 2006-10-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358611-A1 COMPOSITIONS AZI2, NISCH, CIP2A THRB 3748/4885KMT2A 617/4885PLA2G1B 2393/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 THRB 1844/4885KMT2A 804/4885PLA2G1B 3909/4885
US-11116712-B2 Fragrance composition NISCH, CUTA, CYP1B1 THRB 4252/4885KMT2A 1629/4885PLA2G1B 3990/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 THRB 1553/4885KMT2A 2977/4885PLA2G1B 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.