SCHEMBL3436640

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10049034	0.85	ALDH1A1 (0.50)	CTSAHSP90AA1HSP90AB1LMNAMAPK1
	SCHEMBL3435435	0.83	ALPL (0.58)	CTSAHSP90AB1ALPLALDH1A1L3MBTL1
	SCHEMBL14800013	0.82	HSP90AA1 (0.43)	CTSAHSP90AA1HSP90AB1LMNAMAPK1
	SCHEMBL3436241	0.79	KDM4E (0.38)	CTSAHSP90AA1LMNAALDH1A1KDM4E
	SCHEMBL3437704	0.78	LMNA (0.37)	CTSALMNAMAPK1PIK3CAMAPK8
	SCHEMBL3436812	0.76	HSP90AA1 (0.46)	CTSAHSP90AA1HSP90AB1LMNAMAPK1
	SCHEMBL6734941	0.73	ALPL (0.56)	ALPLKDM4ECNR1
	SCHEMBL14800326	0.72	ADORA3 (0.37)	CTSAHSP90AA1HSP90AB1LMNAMAPK1
	SCHEMBL4345662	0.71	KDM4E (0.62)	LMNAALDH1A1KCNMA1KDM4EHPGD
	SCHEMBL16261149	0.71	LMNA (0.72)	LMNAALDH1A1L3MBTL1KCNMA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.