SCHEMBL3437289

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3437290	0.94	CA12 (0.41)	THRBCA12CA4CA6CA5A
	SCHEMBL3437304	0.92	CA12 (0.43)	CA12CA4CA6CA5ACA7
	SCHEMBL18324420	0.91	CA12 (0.46)	THRBCA12CA4CA6CA5A
	SCHEMBL3437298	0.89	TTR (0.43)	THRBCA12CA4CA6CA5A
	SCHEMBL18194807	0.89	THRB (0.44)	THRBAPPTDP1CYP2C19
	SCHEMBL18324435	0.88	POLB (0.41)	CA12CA4CA6CA5ACA7
	SCHEMBL3437288	0.86	MET (0.47)	THRBCA12CA4CA6CA5A
	SCHEMBL3437303	0.86	MET (0.47)	THRBCA12CA4CA6CA5A
	SCHEMBL3437308	0.84	CA12 (0.49)	THRBCA12CA4CA6CA5A
	SCHEMBL18902062	0.84	CA12 (0.38)	CA12CA4CA6CA5ACA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.