Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046433 | 0.91 | MDM4 (0.58) | CETPMDM4TP53MDM2L3MBTL1 | |
| SCHEMBL3438875 | 0.80 | TDP1 (0.39) | CETPMDM4TP53MDM2L3MBTL1 | |
| SCHEMBL10073852 | 0.75 | TSHR (0.43) | CETPMDM4TP53L3MBTL1LMNA | |
| SCHEMBL12666623 | 0.72 | ALDH1A1 (0.66) | CETPMDM4TP53MDM2L3MBTL1 | |
| SCHEMBL20761408 | 0.72 | MDM4 (0.77) | CETPMDM4TP53MDM2L3MBTL1 | |
| SCHEMBL3438880 | 0.71 | HTT (0.50) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL11737069 | 0.71 | MDM4 (0.63) | CETPMDM4TP53MDM2L3MBTL1 | |
| SCHEMBL10046434 | 0.71 | SMN1; SMN2 (0.58) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL16330054 | 0.71 | TP53 (0.63) | CETPMDM4TP53MDM2L3MBTL1 | |
| SCHEMBL3438878 | 0.70 | CETP (0.58) | CETPTP53L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | NATIONAL SCIENCE FOUNDATION | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | DOHH, AOC1, ESD | CETP 4882/4885MDM4 1994/4885TP53 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.