Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229166 | 0.81 | NOTUM (0.47) | NOTUMF2MAPTKDM4EADORA3 | |
| SCHEMBL1896258 | 0.81 | NOTUM (0.47) | NOTUMMAPTKDM4EADORA3RAB9A | |
| SCHEMBL2751218 | 0.80 | NOTUM (0.51) | NOTUMRAB9AKCNH2NPC1 | |
| SCHEMBL69609 | 0.80 | NOTUM (0.39) | NOTUMMAPTKDM4EADORA3ADORA2A | |
| SCHEMBL17797079 | 0.79 | POLB (0.50) | POLB | |
| SCHEMBL2753518 | 0.78 | NOTUM (0.42) | NOTUM | |
| SCHEMBL16719635 | 0.78 | MAOA (0.39) | NOTUMMAPTKDM4EFLT3GSK3B | |
| SCHEMBL17710277 | 0.77 | KCNH2 (0.41) | NOTUMKCNH2 | |
| SCHEMBL7221616 | 0.76 | HTT (0.44) | ADORA3ADORA2ARAB9ACYP1A2MGLL | |
| SCHEMBL7227796 | 0.76 | NOTUM (0.54) | NOTUMMAPTFLT3GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247811-A1 | BICYCLO[1.1.1]PENTANE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-09-27 | — | — | EP | claimed |
| US-20230278997-A1 | BICYCLO[1.1.1]PENTANE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-09-07 | — | — | US | claimed |
| CN-116406359-A | Bicyclo [1.1.1] pentanes for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2023-07-07 | — | — | CN | claimed |
| WO-2022106375-A1 | BICYCLO[1.1.1]PENTANE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-05-27 | — | — | WO | claimed |
| US-11242320-B2 | Process for the preparation of Pyraclostrobin | GSP CROP SCIENCE PVT. LTD. (IN) | 2022-02-08 | — | — | US | claimed |
| US-20200354322-A1 | IMPROVED PROCESS FOR THE PREPARATION OF PYRACLOSTROBIN | GSP CROP SCIENCE PVT. LTD (IN) | 2020-11-12 | — | — | US | claimed |
| CN-110461854-A | Process for preparing chiral 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds | BASF SE | 2019-11-15 | — | — | CN | claimed |
| WO-2019142107-A1 | IMPROVED PROCESS FOR THE PREPARATION OF PYRACLOSTROBIN | GSP CROP SCIENCE PVT. LTD. (IN) | 2019-07-25 | — | — | WO | claimed |
| CN-106117143-B | A kind of preparation method of pyraclostrobin | 青岛瀚生生物科技股份有限公司 | 2019-01-08 | — | — | CN | claimed |
| CN-109068645-A | Mixtures and compositions comprising a paenibacillus strain or fusaricidin and a chemical pesticide | 巴斯夫欧洲公司 | 2018-12-21 | — | — | CN | claimed |
| WO-2007101547-A2 | SYNERGISTIC COMBINATIONS OF ACTIVE INGREDIENTS | BAYER CROPSCIENCE AG (DE) | 2007-09-13 | — | — | WO | claimed |
| CN-101026960-A | Fungicidal mixtures of thiophene derivative | DU PONT (US) | 2007-08-29 | — | — | CN | claimed |
| EP-1802197-A1 | FUNGICIDAL COMBINATIONS OF ACTIVE INGREDIENTS | Bayer CropScience Aktiengesellschaft (DE) | 2007-07-04 | — | — | EP | claimed |
| WO-2007031141-A1 | SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING A CARBOXAMIDE, AN AZOLE, A SECOND AZOLE OR A STROBILURINE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | WO | claimed |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| WO-2007027959-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-08 | — | — | WO | claimed |
| US-20070049556-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-01 | — | — | US | claimed |
| WO-2006131246-A1 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | claimed |
| CN-1870895-A | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2006-11-29 | — | — | CN | claimed |
| WO-2006040016-A1 | FUNGICIDAL COMBINATIONS OF ACTIVE INGREDIENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-04-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354322-A1 | IMPROVED PROCESS FOR THE PREPARATION OF PYRACLOSTROBIN | HPD, HPN, CPB1 | NOTUM 408/4885F2 1803/4885MAPT 4428/4885 |
| US-11242320-B2 | Process for the preparation of Pyraclostrobin | HPD, HPN, PPP3CB | NOTUM 267/4885F2 1639/4885MAPT 4378/4885 |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | CYP51A1, CYP1A2, CYP4X1 | NOTUM 200/4885F2 3391/4885MAPT 4345/4885 |
| US-20070049556-A1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | KCNJ2, KCNN1, KCNN3 | NOTUM 2985/4885F2 3875/4885MAPT 1180/4885 |
| US-20230278997-A1 | BICYCLO[1.1.1]PENTANE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, CYP1B1, CYP7A1 | NOTUM 1768/4885F2 163/4885MAPT 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.