SCHEMBL3440306

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3441075	0.83	CHEK1 (0.51)	NPC1RAB9ASMN1; SMN2MAPK14SMO
	SCHEMBL3441993	0.76	BRD4 (0.60)	NPC1RAB9ASMN1; SMN2MAPTATM
	SCHEMBL21051588	0.75	PTGS1 (0.51)	NPC1RAB9ASMN1; SMN2MAPTMKNK1
	SCHEMBL15676777	0.75	NQO2 (0.47)	HPGD
	SCHEMBL22434984	0.75	NPC1 (0.53)	NPC1RAB9ASMN1; SMN2MAPTATM
	SCHEMBL3440220	0.74	ATM (0.51)	PLK1NPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL20086721	0.72	NPC1 (0.38)	NPC1RAB9ASMN1; SMN2MAPTATM
	SCHEMBL16700744	0.72	KDM4E (0.46)	NPC1RAB9ASMN1; SMN2MAPTHTT
	SCHEMBL13680501	0.72	GRM5 (0.52)	PLK1NPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL16198923	0.72	HDAC6 (0.70)	PLK1NPC1RAB9ASMN1; SMN2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.