SCHEMBL344326

SCHEMBL344326

CON=C(C(=O)NCCc1ccc(OC)c(OC)c1)c1ccc(C)cc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
THRB P10828 1/20 0.65
MAPT P10636 3/20 0.56
LMNA P02545 4/20 0.55
KMT2A Q03164 2/20 0.55
GAA P10253 1/20 0.55
PKM P14618 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
POLB P06746 2/20 0.54
MEN1 O00255 1/20 0.54
ADRB2 P07550 1/20 0.53
ADRB1 P08588 1/20 0.53
ADRB3 P13945 1/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344325 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL344511 0.91 ALDH1A1 (0.55) ALDH1A1THRBMAPTGAACA12
SCHEMBL344512 0.91 ALDH1A1 (0.55) ALDH1A1THRBMAPTGAACA12
SCHEMBL344011 0.90 GAA (0.69) ALDH1A1THRBMAPTLMNAGAA
SCHEMBL344012 0.90 GAA (0.69) ALDH1A1THRBMAPTLMNAGAA
SCHEMBL343887 0.90 ALDH1A1 (0.62) ALDH1A1THRBMAPTGAACA12
SCHEMBL343888 0.90 ALDH1A1 (0.62) ALDH1A1THRBMAPTGAACA12
SCHEMBL27975758 0.90 ALDH1A1 (0.54) ALDH1A1THRBMAPTKMT2AGAA
SCHEMBL19718589 0.90 ALDH1A1 (0.69) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL6816615 0.89 ALDH1A1 (0.54) ALDH1A1THRBMAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160150785-A1 Synergistic Fungicidal Active Substance Combinations BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-06-02 US claimed
WO-2014170354-A1 INSECTICIDAL AND/OR FUNGICIDAL SYNERGISTIC COMBINATIONS OF PHTHALDIAMIDE DERIVATIVES AND A FURTHER ACTIVE INGREDIENT BAYER CROPSCIENCE AG (DE) 2014-10-23 WO claimed
US-20140213557-A1 Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2014-07-31 US claimed
US-20130196981-A1 Synergistic Fungicidal Active Substance Combinations BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-01 US claimed
EP-2023724-B8 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2012-06-06 EP claimed
EP-2453750-A2 SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS CONTAINING PHENYL TRIAZOLES Bayer CropScience AG (DE) 2012-05-23 EP claimed
US-20120015910-A1 Synergistic fungicidal active substance combinations BAYER CROPSCIENCE AG (DE) 2012-01-19 US claimed
US-20110166109-A1 Synergistic Active Compound Combinations Comprising Phenyltriazoles BAYER CROPSCIENCE AG (DE) 2011-07-07 US claimed
US-20110152097-A1 Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2011-06-23 US claimed
WO-2011006603-A2 SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS CONTAINING PHENYL TRIAZOLES BAYER CROPSCIENCE AG (DE) 2011-01-20 WO claimed
EP-2132989-A2 Agent combinations Bayer CropScience AG (DE) 2009-12-16 EP claimed
EP-2124557-A2 SYNERGISTIC FUNGICIDAL COMBINATIONS COMPRISING FORMONONETIN Bayer CropScience AG (DE) 2009-12-02 EP claimed
US-20090280981-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2009-11-12 US claimed
EP-2023724-A2 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS Bayer CropScience Aktiengesellschaft (DE) 2009-02-18 EP claimed
WO-2009012907-A1 SYNERGISTIC FUNGICIDAL ACTIVE GENISTEIN COMBINATIONS BAYER CROPSCIENCE AG (DE) 2009-01-29 WO claimed
US-20090018015-A1 Synergistic Fungicidal Active Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-01-15 US claimed
WO-2008092580-A2 SYNERGISTIC FUNGICIDAL COMBINATIONS COMPRISING FORMONONETIN BAYER CROPSCIENCE AG (DE) 2008-08-07 WO claimed
WO-2007134778-A2 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2007-11-29 WO claimed
WO-2007101547-A2 SYNERGISTIC COMBINATIONS OF ACTIVE INGREDIENTS BAYER CROPSCIENCE AG (DE) 2007-09-13 WO claimed
US-20070060579-A1 Synergistic fungicidal active substance combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152097-A1 Active Compound Combinations AGXT, GLUL, GMNN ALDH1A1 4519/4885THRB 1563/4885MAPT 415/4885
US-20090018015-A1 Synergistic Fungicidal Active Combinations CYP51A1, CYP1A2, CYP3A7 ALDH1A1 241/4885THRB 3858/4885MAPT 4438/4885
US-20160150785-A1 Synergistic Fungicidal Active Substance Combinations CYP1A2, CAT, CYP51A1 ALDH1A1 148/4885THRB 2297/4885MAPT 4339/4885
US-20140213557-A1 Active Compound Combinations AGXT, GLUL, GMNN ALDH1A1 4519/4885THRB 1563/4885MAPT 415/4885
US-20110166109-A1 Synergistic Active Compound Combinations Comprising Phenyltriazoles NAT1, ACAT1, CAT ALDH1A1 972/4885THRB 915/4885MAPT 243/4885
US-20070060579-A1 Synergistic fungicidal active substance combinations CYP51A1, CYP1A2, CYP4X1 ALDH1A1 106/4885THRB 2182/4885MAPT 4345/4885
US-20120015910-A1 Synergistic fungicidal active substance combinations CYP51A1, CYP1A2, CYP4X1 ALDH1A1 106/4885THRB 2182/4885MAPT 4345/4885
US-20130196981-A1 Synergistic Fungicidal Active Substance Combinations CYP51A1, CYP1A2, CYP4X1 ALDH1A1 106/4885THRB 2182/4885MAPT 4345/4885
US-20090280981-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS CYP51A1, ERG28, CYP4X1 ALDH1A1 2224/4885THRB 4192/4885MAPT 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.