SCHEMBL344546

SCHEMBL344546

CC(C)(C)OC(=O)NC1CCC(CO)CC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.50
BTK Q06187 1/20 0.50
EPHX1 P07099 1/20 0.48
KDM1A O60341 1/20 0.47
MAOB P27338 1/20 0.47
CTSK P43235 2/20 0.47
DRD3 P35462 1/20 0.46
GAA P10253 2/20 0.45
NR1H2 P55055 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL944231 1.00 DRD2 (0.50) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL17733738 1.00 DRD2 (0.50) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL343563 1.00 DRD2 (0.50) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL25018554 0.94 BTK (0.56) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL1155174 0.90 BTK (0.55) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL3901032 0.90 BTK (0.55) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL3906349 0.90 BTK (0.55) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL3903151 0.90 BTK (0.55) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL19156343 0.90 BTK (0.55) DRD2BTKEPHX1KDM1AMAOB
SCHEMBL6510047 0.90 BTK (0.55) DRD2BTKEPHX1KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114426504-A Preparation method of trans- (N-4-Boc-aminocyclohexane) acetic acid 泰州精英化成医药科技有限公司 2022-05-03 CN claimed
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 US disclosed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
EP-4107164-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
US-12390451-B2 Small molecule inhibitor of the JAK family of kinases JANSSEN PHARMACEUTICA NV (BE) 2025-08-19 US disclosed
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT ABBVIE INC (US) 2025-05-22 US disclosed
US-12264173-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2025-04-01 US disclosed
US-12202831-B2 Small molecule inhibitors of the JAK family of kinases JANSSEN PHARMACEUTICA NV (BE) 2025-01-21 US disclosed
US-20250019364-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2025-01-16 US disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 EP disclosed
US-20030119855-A1 Heterocycle derivatives and drugs NIPPON SHINYAKU CO., LTD. (JP) 2003-06-26 US disclosed
EP-1306372-A1 HETEROCYCLE DERIVATIVES AND DRUGS Nippon Shinyaku Co., Ltd. (JP) 2003-05-02 EP disclosed
WO-2003028641-A2 MCH RECEPTOR ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2003-04-10 WO disclosed
US-20020193382-A1 Sulfonamide derivatives, their production and use TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) 2002-12-19 US disclosed
WO-2002079151-A1 3-SUBSTITUTED INDOELS OR FUSED PYRROLES AS ANTAGONISTS OF THE CHEMOKINE MCP-1 (CCR2B) RECEPTOR SMITHKLINE BEECHAM P.L.C. (GB) 2002-10-10 WO disclosed
US-6403595-B1 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-11 US disclosed
EP-0798298-B1 THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT SANKYO CO (JP) 2001-08-08 EP disclosed
EP-1054005-A1 SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-22 EP disclosed
US-5843973-A Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient SANKYO COMPANY, LIMITED (JP) 1998-12-01 US disclosed
EP-0798298-A1 THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT SANKYO COMPANY LIMITED (JP) 1997-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 DRD2 1755/4885BTK 2680/4885EPHX1 1627/4885
US-12390451-B2 Small molecule inhibitor of the JAK family of kinases JAK2, JAK1, JAK3 DRD2 4630/4885BTK 26/4885EPHX1 4114/4885
US-12264173-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 DRD2 2140/4885BTK 4051/4885EPHX1 2027/4885
US-20030119855-A1 Heterocycle derivatives and drugs OPRL1, OPRK1, OPRD1 DRD2 382/4885BTK 673/4885EPHX1 1204/4885
US-20250019364-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 DRD2 4680/4885BTK 2336/4885EPHX1 3897/4885
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT BCL2, BAX, BCL2L1 DRD2 3630/4885BTK 3853/4885EPHX1 4831/4885
US-20020193382-A1 Sulfonamide derivatives, their production and use F12, F11, F2 DRD2 1934/4885BTK 142/4885EPHX1 1156/4885
US-12202831-B2 Small molecule inhibitors of the JAK family of kinases JAK1, JAK2, JAK3 DRD2 3323/4885BTK 11/4885EPHX1 3341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.