Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.50 |
| ▸ | CASP1 | P29466 | 8/20 | 0.50 |
| ▸ | CASP7 | P55210 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462336 | 0.90 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL34462349 | 0.88 | MERTK (0.44) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL34462323 | 0.80 | ADORA3 (0.43) | ALDH1A1TSHRADORA3ADORA2BUSP2 | |
| SCHEMBL34462303 | 0.69 | ALDH1A1 (0.35) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL34462228 | 0.69 | CYP1A2 (0.46) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL34462183 | 0.67 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL13036892 | 0.65 | OPRM1 (0.65) | ADORA3ADORA2B | |
| SCHEMBL25428706 | 0.64 | ADORA3 (0.45) | ALDH1A1CLK4ADORA3ADORA2BMEN1 | |
| SCHEMBL30381862 | 0.64 | ADORA3 (0.45) | ALDH1A1CLK4ADORA3ADORA2BMEN1 | |
| SCHEMBL722835 | 0.64 | ADORA3 (0.54) | ALDH1A1CYP2C9CYP2C19TSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |