Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468592 | 0.89 | LMNA (0.68) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL34468614 | 0.78 | ALDH1A1 (0.79) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8288732 | 0.78 | POLB (0.78) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL11376733 | 0.77 | ALDH1A1 (0.77) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL7435098 | 0.75 | L3MBTL1 (0.77) | ALDH1A1MAPTHPGDLMNAGAA | |
| SCHEMBL34468610 | 0.74 | TP53 (0.67) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL34468526 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL7443348 | 0.73 | KMT2A (0.70) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL11356974 | 0.72 | ALDH1A1 (0.75) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL10406531 | 0.72 | KMT2A (0.75) | ALDH1A1MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | claimed |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | SRR, APEH, OSR1 | ALDH1A1 2701/4885MAPT 4472/4885MEN1 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.