SCHEMBL3448177

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3451567	0.89	EGFR (0.44)	PTK2RIPK2EGFRBTKCDK9
	SCHEMBL3452879	0.85	PTK2 (0.38)	PTK2CDK9CDK2CCNT1CCNE1
	SCHEMBL3448178	0.83	PTK2 (0.39)	PTK2RIPK2EGFRBTKCDK9
	SCHEMBL3452002	0.82	THRB (0.46)	PTK2RIPK2CDK9AURKAMAP4K4
	SCHEMBL3452005	0.82	THRB (0.46)	PTK2RIPK2CDK9AURKAMAP4K4
	SCHEMBL3448175	0.79	KDM4E (0.42)	PTK2RIPK2HDAC3HDAC1HDAC2
	SCHEMBL3449925	0.73	SYK (0.42)	PTK2RIPK2EGFRBTKCDK2
	SCHEMBL3451325	0.72	SYK (0.42)	PTK2RIPK2EGFRBTKACVR1
	SCHEMBL3451569	0.71	RIPK2 (0.43)	PTK2RIPK2EGFRBTKCDK9
	SCHEMBL3449534	0.70	RIPK2 (0.45)	PTK2RIPK2CDK9AURKAMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.