SCHEMBL3448178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3451569	0.88	RIPK2 (0.43)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3452002	0.86	THRB (0.46)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3452005	0.86	THRB (0.46)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3452880	0.85	PTGS2 (0.38)	PTK2CDK9JAK3GAKPTGS2
	SCHEMBL3448175	0.84	KDM4E (0.42)	PTK2RIPK2MAPK1
	SCHEMBL3448177	0.83	PTK2 (0.40)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3449538	0.74	RIPK2 (0.45)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3449534	0.74	RIPK2 (0.45)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3451566	0.73	RIPK2 (0.41)	PTK2RIPK2CDK9KDRGSK3A
	SCHEMBL3449929	0.72	SYK (0.43)	PTK2RIPK2ACVR1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.