SCHEMBL3448582

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3447266	0.95	ALDH1A1 (0.46)	ASIC3ALDH1A1CYP3A4HSD17B10HPGD
	SCHEMBL31026479	0.95	ALDH1A1 (0.46)	ASIC3ALDH1A1CYP3A4HSD17B10HPGD
	SCHEMBL5572006	0.78	ASIC3 (0.52)	ASIC3ALDH1A1CYP3A4HSD17B10CYP1A2
	SCHEMBL5573818	0.78	ASIC3 (0.52)	ASIC3ALDH1A1CYP3A4HSD17B10CYP1A2
	SCHEMBL8628482	0.77	ASIC3 (0.61)	ASIC3ALDH1A1CYP3A4HSD17B10CYP1A2
	SCHEMBL29429053	0.77	APP (0.55)	ASIC3ALDH1A1CYP3A4HSD17B10HPGD
	SCHEMBL430978	0.77	ASIC3 (0.61)	ASIC3ALDH1A1CYP3A4HSD17B10CYP1A2
	SCHEMBL28797622	0.76	ALDH1A1 (0.50)	ASIC3ALDH1A1CYP3A4HSD17B10HPGD
	SCHEMBL929237	0.76	APP (0.52)	ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
	SCHEMBL3446999	0.72	ALDH1A1 (0.38)	ALDH1A1CYP3A4HSD17B10HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.