Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8224071 | 1.00 | EPHX2 (0.42) | EPHX2CES2CES1NAAAEPHX1 | |
| SCHEMBL19012246 | 0.89 | — | — | |
| SCHEMBL24221648 | 0.89 | NPSR1 (0.37) | EPHX2EPHX1GAA | |
| SCHEMBL12838113 | 0.89 | — | — | |
| SCHEMBL805266 | 0.89 | — | — | |
| SCHEMBL5909767 | 0.85 | CES2 (0.41) | CES2CES1NAAAEPHX1HSD11B1 | |
| SCHEMBL18597007 | 0.83 | NAAA (0.38) | CES2CES1NAAAEPHX1HSD11B1 | |
| SCHEMBL18494027 | 0.83 | NPSR1 (0.34) | EPHX2EPHX1GAA | |
| SCHEMBL3787105 | 0.81 | POLB (0.38) | GAAALDH1A1 | |
| SCHEMBL7183407 | 0.80 | KDM4E (0.31) | EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1316582-B1 | POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES | KURARAY CO (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
| US-7820261-B2 | Polyvinyl alcohol resin composition and multilayer packages | KURARAY CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20070243351-A1 | POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES | KURARAY CO. LTD. (JP) | 2007-10-18 | — | — | US | disclosed |
| US-7255904-B2 | Polyvinyl alcohol resin composition and multilayer packages | KURARAY CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1316582-A1 | POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES | KURARAY CO., LTD. (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-20030022974-A1 | Polyvinyl alcohol resin composition and multilayer packages | KURARAY CO., LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | HAMP, SLC40A1, FTH1 | EPHX2 323/4885CES2 4310/4885CES1 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.