SCHEMBL3450779

SCHEMBL3450779

O=C(c1ccc(CCl)cc1)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.64
HDAC6 Q9UBN7 2/20 0.64
HDAC3 O15379 1/20 0.64
HDAC7 Q8WUI4 1/20 0.64
HDAC10 Q969S8 1/20 0.64
HDAC8 Q9BY41 1/20 0.64
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
CRHBP P24387 1/20 0.59
CRHR2 Q13324 1/20 0.59
TSHR P16473 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TDP1 Q9NUW8 1/20 0.51
KDM4E B2RXH2 1/20 0.51
RCE1 Q9Y256 1/20 0.51
LPAR1 Q92633 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3178210 0.90 HDAC1 (0.65) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL8359492 0.89 KMT2A (0.76) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL1003508 0.85 HDAC1 (0.71) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL8359489 0.83 KMT2A (0.69) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL6843722 0.81 ALDH1A1 (0.68) HDAC1HDAC6HDAC3HDAC7HDAC10
Oxalic Acid SCHEMBL29264737 0.81 HDAC1 (0.67) HDAC1HDAC6HDAC3HDAC7HDAC10
Oxalic Acid SCHEMBL29264739 0.81 HDAC1 (0.67) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL28778954 0.80 KMT2A (0.65) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL3456064 0.80 KMT2A (0.70) HDAC1HDAC6HDAC3HDAC7HDAC10
SCHEMBL28681773 0.80 KMT2A (0.65) HDAC1HDAC6HDAC3HDAC7HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109305949-B Monomer, polymer, compensation film, optical film and display device 三星电子株式会社 2023-08-15 CN disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 US disclosed
EP-3438156-B1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-04-22 EP disclosed
EP-3438156-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE Samsung Electronics Co., Ltd. (KR) 2019-02-06 EP disclosed
US-20190031831-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-01-31 US disclosed
US-7820837-B2 ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-10-26 US disclosed
US-20060258722-A1 Condensed ring compound TAKEDA PHARMACEUTICAL COMPANY., LTD. (JP) 2006-11-16 US disclosed
EP-1630152-A1 CONDENSED RING COMPOUND Takeda Pharmaceutical Company Limited (JP) 2006-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031831-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE RAP1A, PYM1, COL1A1 HDAC1 3146/4885HDAC6 4630/4885HDAC3 4868/4885
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE PYM1, PADI1, COL1A1 HDAC1 3783/4885HDAC6 4805/4885HDAC3 4884/4885
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device PYM1, PADI1, COL1A1 HDAC1 3783/4885HDAC6 4805/4885HDAC3 4884/4885
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device RAP1A, PYM1, COL1A1 HDAC1 3146/4885HDAC6 4630/4885HDAC3 4868/4885
US-20060258722-A1 Condensed ring compound GPR119, GLP1R, GCGR HDAC1 385/4885HDAC6 776/4885HDAC3 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.