Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781586 | 0.78 | OPRM1 (0.37) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL21615892 | 0.75 | PDK2 (0.39) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3840448 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28576602 | 0.73 | SLC6A2 (0.40) | ALDH1A1RAB9A | |
| SCHEMBL11233815 | 0.72 | METAP2 (0.39) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29818101 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30620546 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL7226244 | 0.71 | PARP1 (0.50) | NPC1PARP1 | |
| SCHEMBL29817953 | 0.71 | SIRT1 (0.43) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11119681 | 0.71 | METAP2 (0.38) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820830-B2 | Process for the production of carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| EP-1951677-B1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080262242-A1 | Process For the Production of Carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1951677-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | Syngeta Participations AG (CH) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057140-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262242-A1 | Process For the Production of Carboxanilides | FGFR2, FGFR4, CCKBR | KDM4E 1349/4885ALDH1A1 1759/4885MAPT 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.