Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451774 | 0.75 | KDM4E (0.42) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29065566 | 0.72 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3840448 | 0.70 | KDM4E (0.45) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6659416 | 0.70 | OPRL1 (0.56) | ALDH1A1OPRL1OPRM1 | |
| SCHEMBL6659407 | 0.70 | OPRL1 (0.56) | ALDH1A1OPRL1OPRM1 | |
| SCHEMBL6659414 | 0.70 | OPRL1 (0.56) | ALDH1A1OPRL1OPRM1 | |
| SCHEMBL17786074 | 0.69 | PDK2 (0.40) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11259349 | 0.69 | OPRL1 (0.48) | OPRL1OPRM1 | |
| SCHEMBL11233815 | 0.69 | METAP2 (0.39) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7226244 | 0.68 | PARP1 (0.50) | PARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380575-A1 | DRUG CONJUGATES OF SUGAR DERIVATIVES AND USES THEREOF AS SENOLYTIC AGENTS | Rubedo Life Sciences, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | Rubedo Life Sciences, Inc. | 2023-10-12 | — | — | US | disclosed |
| US-20230137021-A1 | Drug Conjugates of Sugar Derivatives and Uses Thereof as Senolytic Agents | Rubedo Life Sciences, Inc. | 2023-05-04 | — | — | US | disclosed |
| WO-2023039600-A1 | DRUG CONJUGATES OF SUGAR DERIVATIVES AND USES THEREOF AS SENOLYTIC AGENTS | Rubedo Life Sciences, Inc. (US) | 2023-03-16 | — | — | WO | disclosed |
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | Rubedo Life Sciences, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-11026963-B2 | Senolytic compositions and uses thereof | Rubedo Life Sciences, Inc. (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3790861-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. (US) | 2021-03-17 | — | — | EP | disclosed |
| CN-112469697-A | Anti-aging composition and application thereof | 鲁贝多生命科学公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. | 2020-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299154-A1 | Senolytic Compositions And Uses Thereof | SENP3, SENP6, SENP1 | PDK2 405/4885KDM4E 4172/4885ALDH1A1 1807/4885 |
| US-11026963-B2 | Senolytic compositions and uses thereof | SENP3, SENP6, SENP1 | PDK2 405/4885KDM4E 4172/4885ALDH1A1 1807/4885 |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | SENP3, SENP6, SENP1 | PDK2 405/4885KDM4E 4172/4885ALDH1A1 1807/4885 |
| US-20230137021-A1 | Drug Conjugates of Sugar Derivatives and Uses Thereof as Senolytic Agents | AGER, SENP6, SENP3 | PDK2 131/4885KDM4E 3425/4885ALDH1A1 748/4885 |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | SENP3, SENP6, SENP1 | PDK2 405/4885KDM4E 4172/4885ALDH1A1 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.