Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595757 | 0.82 | MAPK10 (0.39) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL12571335 | 0.77 | MAPK10 (0.41) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL15096829 | 0.77 | MAPK10 (0.41) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL208785 | 0.75 | CTSK (0.42) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL5729371 | 0.75 | CTSK (0.42) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL27733205 | 0.73 | MAPK10 (0.39) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL4774889 | 0.73 | MAPK10 (0.42) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL8317089 | 0.73 | MAPK10 (0.39) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL1140993 | 0.73 | MAPK10 (0.39) | TDP1MAPK10APLNRCTSKDGAT1 | |
| SCHEMBL166623 | 0.71 | CA1 (0.42) | TDP1MAPK10APLNRCTSKDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047079-B1 | NONAPEPTIDES AFFECTING GONADAL FUNCTION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1984-02-22 | — | — | EP | claimed |
| US-4382922-A | Peptides affecting gonadal function | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1983-05-10 | — | — | US | claimed |
| EP-0021620-B1 | WATER-SOLUBLE PEPTIDES AFFECTING GONADAL FUNCTION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1983-02-23 | — | — | EP | claimed |
| US-4244946-A | LUTEINIZING-HORMONE RELEASING FACTOR AGONISTS AS ANTIFERTILITY AGENTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1981-01-13 | — | — | US | claimed |
| EP-0021620-A1 | Water-soluble peptides affecting gonadal function | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1981-01-07 | — | — | EP | claimed |
| US-7820831-B2 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | RHODIA OPERATIONS (FR) | 2008-12-11 | — | — | US | disclosed |
| US-7423161-B2 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2008-09-09 | — | — | US | disclosed |
| EP-0604957-B1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0624163-B1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMA (IT) | 1998-03-25 | — | — | EP | disclosed |
| US-5508382-A | SYNTHETIC CALCITONIN | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5506267-A | IMMUNOADJUVANT FOR BONE MARROW CELL GROWTH AFTERTREATMENT OF CHEMOTHERAPY OR RADIOTHERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-4159981-A | CYCLIC POLYPEPTIDES, DEETHERIFICATION, DEESTERIFICATION | CIBA-GEIGY CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-4086221-A | SERUM CALCIUM REDUCING ACTIVITY | TOYO JOZO KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4018726-A | [D-Phe6 ]-LH-RH and intermediates therefor | SCHALLY ANDREW VICTOR | 1977-04-19 | — | — | US | disclosed |
| US-4010125-A | [D-Trp6 ]-LH-RH and intermediates therefor | SCHALLY ANDREW VICTOR | 1977-03-01 | — | — | US | disclosed |
| US-3994871-A | Process for the manufacture of peptides containing cystine | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3971737-A | [2-Methyl-Ala6 ]LRH | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
| US-3956260-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3934008-A | PEPTIDES, HYPOCALCAEMIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | PFAS, SULT1A1, CYP2F1 | TDP1 3009/4885MAPK10 3698/4885APLNR 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.