Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455841 | 0.81 | KMT2A (0.58) | ALDH1A1GAARAB9AMAPTKMT2A | |
| SCHEMBL5215442 | 0.79 | ALDH1A1 (0.62) | ALDH1A1GAAPOLBMAPK8KDM4E | |
| SCHEMBL7364681 | 0.79 | RAB9A (0.72) | ALDH1A1GAAPOLBRAB9AMAPK8 | |
| SCHEMBL10971064 | 0.77 | ALDH1A1 (0.72) | ALDH1A1GAAPOLBMAPK8MAPT | |
| SCHEMBL11247603 | 0.77 | NPC1 (0.63) | ALDH1A1GAAPOLBRAB9AKDM4E | |
| SCHEMBL2332693 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAAPOLBRAB9APTGER4 | |
| SCHEMBL7674124 | 0.77 | ALDH1A1 (0.58) | ALDH1A1GAAPOLBRAB9APTGER4 | |
| SCHEMBL5214807 | 0.77 | ALDH1A1 (0.65) | ALDH1A1GAAPOLBRAB9AMAPK8 | |
| SCHEMBL10969124 | 0.75 | P2RY1 (0.60) | ALDH1A1GAAPOLBKDM4EMEN1 | |
| SCHEMBL10971738 | 0.75 | KMT2A (0.75) | ALDH1A1GAAPOLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |