Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067369 | 0.75 | MAPT (0.34) | MAPTALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL3454571 | 0.71 | CTSC (0.34) | KDM1A | |
| SCHEMBL3468778 | 0.69 | OPRD1 (0.51) | MAPTALDH1A1HPGD | |
| SCHEMBL3454585 | 0.67 | MAPT (0.34) | MAPTALDH1A1HPGDTSHRPDE3B | |
| SCHEMBL12160700 | 0.60 | ALDH1A1 (0.53) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL17660600 | 0.59 | CDK1 (0.43) | MAPTALDH1A1CDK4SMN1; SMN2CCNE1 | |
| SCHEMBL8257783 | 0.59 | CHRM2 (0.43) | MAPTALDH1A1HPGDTSHRCDK4 | |
| SCHEMBL16249197 | 0.59 | ALDH1A1 (0.51) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL7055201 | 0.58 | HTR7 (0.57) | MAPTALDH1A1LMNA | |
| SCHEMBL13419303 | 0.57 | HTR1A (0.52) | MAPTALDH1A1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166850-A1 | NEW HETEOCYCLIC H3 ANTAGONISTS | High Point Pharmaceuticals, LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154126-A1 | NEW HETEOCYCLIC H3 ANTAGONISTS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2008-12-18 | — | — | WO | disclosed |