Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365213 | 1.00 | KDM1A (0.44) | KDM1AKDM1BKCNH2NPC1RAB9A | |
| SCHEMBL345437 | 0.97 | KDM1A (0.43) | KDM1AKDM1BKCNH2NPC1RAB9A | |
| SCHEMBL505780 | 0.93 | KDM1A (0.48) | KDM1AKDM1BKCNH2NPC1RAB9A | |
| SCHEMBL502648 | 0.89 | KDM1A (0.41) | KDM1AKDM1BKCNH2NPC1RAB9A | |
| SCHEMBL28157241 | 0.86 | KDM1A (0.44) | KDM1AKDM1BKCNH2NPC1RAB9A | |
| SCHEMBL29710388 | 0.85 | AHR (0.39) | KDM1AKDM1BKCNH2CA1CA2 | |
| SCHEMBL733675 | 0.85 | AHR (0.39) | KDM1AKDM1BKCNH2CA1CA2 | |
| Ether SCHEMBL27967823 | 0.80 | HPGD (0.35) | KDM1AKDM1BKCNH2RAB9AKMT2A | |
| Tetrahydrofuran SCHEMBL28812758 | 0.80 | KDM1A (0.38) | KDM1AKDM1BKCNH2MAPTKMT2A | |
| SCHEMBL23539570 | 0.76 | KDM1A (0.48) | KDM1AKDM1BKCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | claimed |
| US-12275734-B1 | Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-04-15 | — | — | US | claimed |
| CN-115819260-B | Synthesis process of sitagliptin intermediate | 江苏阿尔法药业股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-116283539-A | Preparation method of 2,4, 5-trifluoro phenylacetic acid | 安庆朗坤药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-20230183154-A1 | PROCESS FOR THE PREPARATION OF 1-BROMO-2,4,5-TRIFLUOROBENZENE | AARTI INDUSTRIES LIMITED (IN) | 2023-06-15 | — | — | US | claimed |
| CN-116178128-A | Preparation method and application of 3-chloro-2, 4, 5-trifluoro-benzoic acid | 安庆市鑫琪精细化工有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115850018-A | Synthesis method of 1,2, 4-trifluorobenzene | 阜新睿光氟化学有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115819260-A | Synthesis process of sitagliptin intermediate | 江苏阿尔法药业股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| EP-4118065-A1 | PROCESS FOR THE PREPARATION OF 1-BROMO-2,4,5-TRIFLUOROBENZENE | Aarti Industries Limited (IN) | 2023-01-18 | — | — | EP | claimed |
| CN-115551823-A | Preparation method of 1-bromo-2,4,5-trifluorobenzene | 阿尔第实业有限公司 | 2022-12-30 | — | — | CN | claimed |
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1362860-A1 | Method for producing tetrakis (fluoroaryl) borate magnesium compound | Nippon Shokubai Co., Ltd. (JP) | 2003-11-19 | — | — | EP | claimed |
| EP-0838242-B1 | Thermally responsive frangible bulb | TYCO FIRE PRODUCTS MFG LTD (GB) | 2002-06-05 | — | — | EP | claimed |
| US-5967238-A | USED TO AUTOMATICALLY RELEASE QUICK RESPONSE, FIRE PROTECTION SPRINKLERS, LIQUID EXPANDS TO FILL AND FRACTURE THE BULB WHEN HEATED, HALOGEN DERIVATIVE OF AN AROMATIC HYDROCARBON CONTAINING TWO OR MORE HALOGEN SUBSTITUENTS, AN ALIPHATIC | GRINNELL MANUFACTURING (UK) LIMITED (GB) | 1999-10-19 | — | — | US | claimed |
| EP-0667328-B1 | Process for the preparation of aromatic fluoro compounds | CLARIANT GMBH (DE) | 1998-09-16 | — | — | EP | claimed |
| EP-0838242-A2 | Thermally responsive frangible bulb | Grinnell Manufacturing (UK) Limited (GB) | 1998-04-29 | — | — | EP | claimed |
| US-5498807-A | Process for the preparation of aromatic fluoro compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | claimed |
| EP-0667328-A1 | Process for the preparation of aromatic fluoro compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | claimed |
| WO-1995009828-A1 | 2,4,5-TRIFLUOROBENZENES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1995-04-13 | — | — | WO | claimed |
| EP-0302525-A2 | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275734-B1 | Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof | PLEC, PML, MRPL21 | KDM1A 2363/4885KDM1B 3138/4885KCNH2 1872/4885 |
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | KRAS, MGAM, CA3 | KDM1A 4098/4885KDM1B 3691/4885KCNH2 607/4885 |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | PLEC, MLN, MRPL21 | KDM1A 4043/4885KDM1B 4291/4885KCNH2 2015/4885 |
| US-20230183154-A1 | PROCESS FOR THE PREPARATION OF 1-BROMO-2,4,5-TRIFLUOROBENZENE | FLNB, SULT1E1, SPIN2B | KDM1A 855/4885KDM1B 746/4885KCNH2 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.