Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL22191621 | 0.88 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.87 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.87 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.87 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.87 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28700820 | 0.86 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL23581144 | 0.85 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL787168 | 0.85 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL540691 | 0.85 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.83 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250043097-A1 | A METHOD OF RECYCLING PLASTIC WASTE COMPRISING PET | UNIV COLLEGE CORK NATIONAL UNIV OF IRELAND CORK (IE) | 2025-02-06 | — | — | US | claimed |
| CN-119221140-A | Heavy denier, small pore and overweight net DTY fiber and preparation method thereof | 江苏恒科新材料有限公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4444790-A1 | A METHOD OF RECYCLING PLASTIC WASTE COMPRISING PET | University College Cork-National University of Ireland Cork (IE) | 2024-10-16 | — | — | EP | claimed |
| WO-2023105077-A1 | A METHOD OF RECYCLING PLASTIC WASTE COMPRISING PET | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2023-06-15 | — | — | WO | claimed |
| EP-4194490-A1 | A METHOD OF RECYCLING PLASTIC WASTE | University College Cork-National University of Ireland Cork (IE) | 2023-06-14 | — | — | EP | claimed |
| CN-115698125-A | Method for improving L color in PET polymer | 科氏技术英国有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115698123-A | Process for making oligomeric polyethylene terephthalate (PET) substrates | 科氏技术英国有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115698124-A | Process for making oligomeric polyethylene terephthalate (PET) substrates | 科氏技术英国有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115698126-A | Process for making oligomeric polyethylene terephthalate (PET) substrates | 科氏技术英国有限公司 | 2023-02-03 | — | — | CN | claimed |
| US-11359068-B2 | Enzymatic process for depolymerization of post-consumer poly(ethylene terephthalate) by a glycolysis reaction, process for recycling post-consumer poly(ethylene terephthalate), and recycled poly(ethylene terephthalate) | Petroleo Brasileiro S.A.—Petrobras (BR) | 2022-06-14 | — | — | US | claimed |
| US-20200255621-A1 | ENZYMATIC PROCESS FOR DEPOLYMERIZATION OF POST-CONSUMER POLY(ETHYLENE TEREPHTHALATE) BY A GLYCOLYSIS REACTION, PROCESS FOR RECYCLING POST-CONSUMER POLY(ETHYLENE TEREPHTHALATE), AND RECYCLED POLY(ETHYLENE TEREPHTHALATE) | PETROLEO BRASILEIRO S.A. - PETROBRAS (BR) | 2020-08-13 | — | — | US | claimed |
| WO-2019053392-A1 | ENZYMATIC PROCESS FOR DEPOLYMERIZATION OF POST-CONSUMER POLY(ETHYLENE TEREPHTHALATE) BY A GLYCOLYSIS REACTION, PROCESS FOR RECYCLING POST-CONSUMER POLY(ETHYLENE TEREPHTHALATE) AND RECYCLED POLY(ETHYLENE TEREPHTHALATE) | Petróleo Brasileiro S.A. - Petrobras (BR) | 2019-03-21 | — | — | WO | claimed |
| US-9068056-B2 | Method for forming composite materials | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2015-06-30 | — | — | US | claimed |
| US-20110288219-A1 | METHOD FOR FORMING COMPOSITE MATERIALS | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2011-11-24 | — | — | US | claimed |
| US-4010146-A | Polyol blends and polyurethane prepared therefrom | SAMUEL MOORE AND COMPANY (US) | 1977-03-01 | — | — | US | claimed |
| JP-59071325-A | — | — | None | — | — | JP | disclosed |
| JP-10298597-A | — | — | None | — | — | JP | disclosed |
| JP-S5971325-A | PREPARATION OF POLYESTER | TOYOBO CO LTD | 1984-04-23 | — | — | JP | disclosed |
| US-4260817-A | Process for the purification of terephthalic acid | JOHNSON, MATTHEY & CO., LIMITED (GB) | 1981-04-07 | — | — | US | disclosed |
| US-4101439-A | Polyol blends and polyurethane prepared therefrom | SAMUEL MOORE & COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250043097-A1 | A METHOD OF RECYCLING PLASTIC WASTE COMPRISING PET | KIT, PBRM1, PIGO | TSHR 2442/4885TP53 126/4885SRD5A2 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.