SCHEMBL345584

SCHEMBL345584

CCCCC(N)(C(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.36
CTSK P43235 8/20 0.35
CTSS P25774 2/20 0.35
DGAT1 O75907 1/20 0.34
ARG1 P05089 2/20 0.33
ARG2 P78540 2/20 0.33
SMPD1 P17405 3/20 0.32
GGT1 P19440 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9543424 1.00 FDPS (0.36) FDPSCTSKCTSSDGAT1ARG1
Ammonia Solution, Strong SCHEMBL28292145 0.98 FDPS (0.35) FDPSCTSKCTSSDGAT1ARG1
Hydrochloric Acid SCHEMBL28182381 0.98 FDPS (0.35) FDPSCTSKCTSSDGAT1ARG1
SCHEMBL29762781 0.93 SMPD1 (0.40) FDPSSMPD1MEN1ALDH1A1KMT2A
SCHEMBL8001832 0.93 SMPD1 (0.40) FDPSSMPD1MEN1ALDH1A1KMT2A
SCHEMBL17768312 0.93 SMPD1 (0.40) FDPSSMPD1MEN1ALDH1A1KMT2A
SCHEMBL4825036 0.93 SMPD1 (0.40) FDPSSMPD1MEN1ALDH1A1KMT2A
SCHEMBL6372947 0.89 DGAT1 (0.36) FDPSCTSKCTSSDGAT1ARG1
Ammonia Solution, Strong SCHEMBL27708715 0.87 DGAT1 (0.35) FDPSCTSKCTSSDGAT1ARG1
SCHEMBL9016090 0.86 ODC1 (0.42) DGAT1ARG1ARG2GGT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109355310-A ROS (reactive oxygen species) -responsive gene delivery vector as well as preparation method and application thereof 南京工业大学 2019-02-19 CN claimed
CN-107233581-A One kind can carry out the imaging of MR fluorescent dual module states lymph, degradable small particle nano-micelle and its preparation method and application 中山大学 2017-10-10 CN claimed
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2025-07-24 US disclosed
US-20250114448-A1 SAPONIN-BASED ADJUVANTS AND VACCINES ASOCIACION CENTRO DE INVESTIG COOPERATIVA EN BIOCIENCIAS CIC BIOGUNE (ES) 2025-04-10 US disclosed
CN-119661630-A Thixotropic small molecule gel, preparation method and application thereof 西安交通大学 2025-03-21 CN disclosed
EP-4466278-A1 SAPONIN-BASED ADJUVANTS AND VACCINES Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) 2024-11-27 EP disclosed
CN-118930469-A Compound for delivering small nucleic acid to brain cells and application thereof 圣诺生物医药技术(苏州)有限公司 2024-11-12 CN disclosed
CN-114702506-B 11-carbonyl-20-ethoxy source oridonin and 14-OH esterified serial derivatives and application thereof 郑州大学 2023-08-22 CN disclosed
EP-4219518-A2 BIOCONJUGATES OF HETEROCYCLIC COMPOUNDS Taizhou Huifeng Hetai Biotechnology Co. Ltd (CN) 2023-08-02 EP disclosed
WO-2023139145-A1 SAPONIN-BASED ADJUVANTS AND VACCINES ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) 2023-07-27 WO disclosed
US-11464864-B2 Drug-bound compound and use thereof SOONCHUNHYANG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2022-10-11 US disclosed
CN-1080720-C Thiazole derivatives HOFFMANN LA ROCHE (CH) 2002-03-13 CN disclosed
US-6342225-B1 FOR THERAPY OF DIABETES MELLITUS DEUTSHCES WOLLFORSCHUNGSINSTITUT (DE) 2002-01-29 US disclosed
US-6063761-A ANTIDIABETIC AGENTS KINGS COLLEGE LONDON (GB) 2000-05-16 US disclosed
CN-1224718-A Thiazole derivatives HOFFMANN LA ROCHE (CH) 1999-08-04 CN disclosed
US-5854208-A Hepatoselective pharmaceutical actives DEUTSCHES WOLLFORSCHUNGSINSTITUT (DE) 1998-12-29 US disclosed
EP-0725648-A1 HEPATOSELECTIVE PHARMACEUTICAL ACTIVES THE UNITED MEDICAL AND DENTAL SCHOOLS OF GUY'S AND ST. THOMAS'S HOSPITALS (GB) 1996-08-14 EP disclosed
WO-1995005187-A1 HEPATOSELECTIVE PHARMACEUTICAL ACTIVES UNITED MEDICAL & DENTAL SCHOOLS OF GUY'S AND ST THOMAS' HOSPITALS (GB) 1995-02-23 WO disclosed
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed
US-4745124-A THIO/ESTER PEPTIDES UNIVERSITY OF MIAMI (US) 1988-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MUC1, RNMT, FABP2 FDPS 3299/4885CTSK 3500/4885CTSS 4169/4885
US-11464864-B2 Drug-bound compound and use thereof SLC2A9, ABCB1, SLC5A7 FDPS 1640/4885CTSK 4042/4885CTSS 4141/4885
US-20250114448-A1 SAPONIN-BASED ADJUVANTS AND VACCINES STT3A, STT3B, DDOST FDPS 1087/4885CTSK 3989/4885CTSS 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.