Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | BID | P55957 | 3/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15563320 | 0.85 | POLB (0.37) | CYP2D6CYP3A4CYP2C9LIPGPOLB | |
| SCHEMBL15563302 | 0.83 | CYP3A4 (0.39) | CYP2D6CYP3A4CYP2C9LIPGTSHR | |
| SCHEMBL15563153 | 0.83 | CYP3A4 (0.46) | CYP2D6CYP3A4CYP2C9LIPGBID | |
| SCHEMBL15563463 | 0.81 | LIPG (0.49) | CYP2D6CYP3A4CYP2C9LIPGBID | |
| SCHEMBL15563129 | 0.80 | LIPG (0.51) | CYP2D6CYP3A4CYP2C9LIPGBID | |
| SCHEMBL9248747 | 0.79 | LIPG (0.38) | CYP2D6CYP3A4CYP2C9LIPGPOLB | |
| SCHEMBL8113452 | 0.79 | GABRA1 (0.40) | CYP2D6CYP3A4CYP2C9LIPG | |
| SCHEMBL15563144 | 0.78 | CYP3A4 (0.45) | CYP2D6CYP3A4CYP2C9LIPGBID | |
| SCHEMBL15563104 | 0.78 | LIPG (0.49) | CYP2D6CYP3A4CYP2C9LIPGBID | |
| SCHEMBL11014049 | 0.78 | LIPG (0.41) | CYP2D6CYP3A4CYP2C9LIPGBID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263995-A1 | Para-tert-butylcalix[6]arenes with triacid fuctional groups in positions 2, 4 and 6, as well as supported liquid membranes and support material comprising such membranes and their use | INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE (I.R.S.N.) (FR) | 2010-12-22 | — | — | EP | disclosed |
| US-20090095681-A1 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6, SUPPORTED LIQUID MEMBRANES AND SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | CHELATOR (FR) | 2009-04-16 | — | — | US | disclosed |
| EP-1885682-A2 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6 SUPPORTED LIQUID MEMBRANES SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | CHELATOR (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006123051-A2 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6 SUPPORTED LIQUID MEMBRANES SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | CHELATOR (FR) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090095681-A1 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6, SUPPORTED LIQUID MEMBRANES AND SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | TERT, SLC6A6, SLC26A3 | CYP2D6 1034/4885CYP3A4 2368/4885CYP2C9 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.